Russell Paul S S, George Christina, Mammen Priya
Child and Adolescent Psychiatry Unit, Department of Psychiatry, Christian Medical College, Vellore 632 002, India.
Clin Pract Epidemiol Ment Health. 2006 Sep 22;2:25. doi: 10.1186/1745-0179-2-25.
Aim was to determine the predictive factors for polypharmacy among inpatient children and adolescents with psychiatric disorders.
Blinded, case-note review of children and adolescents with ICD 10 diagnosis of psychiatric disorders on psychotropic medication was conducted. Data on demography, illness, and treatment was analyzed with univariate and multivariate techniques.
Proscribing non-pharmacological interventions (OR = 4.7) and pro re nata medication (OR = 3.3), increased the risk of polypharmacy. Prescribing physical restraint reduced the risk of receiving multiple medications (OR = 0.3).
Proscribing non-pharmacological interventions, pro re nata medication and physical restraints increased polypharmacy.
目的是确定患有精神疾病的住院儿童和青少年中多重用药的预测因素。
对接受精神药物治疗且国际疾病分类第10版诊断为精神疾病的儿童和青少年进行盲法病例记录回顾。采用单变量和多变量技术分析人口统计学、疾病和治疗数据。
未采用非药物干预措施（比值比=4.7）和按需给药（比值比=3.3）会增加多重用药风险。采用身体约束措施可降低接受多种药物治疗的风险（比值比=0.3）。
未采用非药物干预措施、按需给药和身体约束措施会增加多重用药情况。
