Renkielska Alicja, Nowakowski Antoni, Kaczmarek Mariusz, Ruminski Jacek
Department of Plastic Surgery and Burns, Medical University of Gdansk, il. Debinki 7, 80-211 Gdansk, Poland.
Burns. 2006 Nov;32(7):867-75. doi: 10.1016/j.burns.2006.01.024. Epub 2006 Sep 25.
Proper diagnostic assessment of burn wound depth is of the highest importance in selecting the mode of burn wound treatment. Several diagnostic methods--clinical and histopathological evaluation, as well as methods employing IR imaging--static thermography and active dynamic thermography (ADT)--are compared on the basis of in vivo experiments conducted on three domestic pigs (23 burn wounds). ADT is presented here as a new, reliable and quantitative method of assessing burn wound depth on the basis of discrimination of the thermal properties of burnt tissue. In the case of ADT registration of thermal images was performed following thermal pulse excitation. A series of captured infrared images was used as the basis for calculating the thermal time constant tau for each pixel. The parameter values were compared with histopathological and clinical assessments of burn depth. The mean value of tau was found for burns, which heal within 3 weeks (tau=12.08+/-1.94s) and for burns, which did not heal during this period (tau=9.07+/-0.68s), p<0.05. The accuracy, sensitivity and specificity of all the methods tested were compared, the best results coming from ADT. The ADT method is fast, non-invasive and relatively inexpensive, although it still requires further animal experimentation as well as clinical study to confirm the results.
正确诊断烧伤创面深度对于选择烧伤创面治疗方式至关重要。基于对三头家猪（23处烧伤创面）进行的体内实验，对几种诊断方法——临床和组织病理学评估以及采用红外成像的方法——静态热成像和主动动态热成像（ADT）进行了比较。本文将ADT作为一种基于区分烧伤组织热特性来评估烧伤创面深度的新的、可靠的定量方法进行介绍。在ADT中，热图像的记录是在热脉冲激发后进行的。一系列捕获的红外图像被用作计算每个像素热时间常数τ的基础。将这些参数值与烧伤深度 的组织病理学和临床评估结果进行比较。发现3周内愈合的烧伤（τ=12.08±1.94秒）和在此期间未愈合的烧伤（τ=9.07±0.68秒）的τ平均值，p<0.05。比较了所有测试方法的准确性、敏感性和特异性，ADT的结果最佳。ADT方法快速、无创且相对便宜，尽管仍需要进一步的动物实验以及临床研究来证实结果。
