Fishman Peter E, Shofer Frances S, Robey Jennifer L, Zogby Kara E, Reilly Patrick M, Branas Charles C, Pines Jesse M, Hollander Judd E
Department of Emergency Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104-4283, USA.
Ann Emerg Med. 2006 Oct;48(4):347-53. doi: 10.1016/j.annemergmed.2006.02.021. Epub 2006 Apr 21.
Trauma systems improve the care of trauma patients; however, it is possible that prioritizing the emergency care of trauma patients might adversely affect other potentially ill patients requiring the same resources. We seek to determine whether the presence of a concurrent trauma activation negatively affects processes of care and outcomes for patients with potential acute coronary syndromes.
Patients who presented to the emergency department (ED) with a potential acute coronary syndrome from July 2003 to June 2004 were stratified according to whether they presented concurrently with a trauma activation. Structured data collection included demographics, medical history, and daily tracking of inhospital course. Thirty-day follow-up was performed. The main outcome was a composite of inhospital cardiovascular complications and 30-day death and myocardial infarction. Secondary outcomes were time from triage to ECG acquisition, transfer to an evaluation room, return of laboratory results, disposition decision, and actual disposition.
Patients who presented concurrently with (n=357) or not concurrently with (n=1,235) a trauma activation were similar with respect to demographic characteristics, cardiac risk factors, and TIMI risk score. The unadjusted incidence of 30-day adverse cardiovascular events between potential acute coronary syndrome patients who presented with and without a concurrent trauma activation was 6.2% versus 3.6% (unadjusted odds ratio 1.74 [95% confidence interval (CI) 1.03 to 2.93]). After adjustment for measures of patient acuity (triage classification, TIMI risk score) and ED volume (total patient care hours and ED activity), concurrent trauma activation was independently associated with increased rate of 30-day cardiovascular complications (odds ratio 1.72; 95% CI 1.01 to 2.92).
The presence of a concurrent trauma activation at the time of presentation of a patient with potential acute coronary syndrome was associated with an increased incidence of 30-day adverse cardiovascular events. Although trauma activations improve the care of trauma patients, they may be associated with a negative impact on the care of other patients requiring contemporaneous resources.
创伤系统可改善创伤患者的治疗;然而,优先处理创伤患者的急诊情况可能会对需要相同资源的其他潜在患病患者产生不利影响。我们试图确定同时发生的创伤激活是否会对潜在急性冠状动脉综合征患者的治疗过程和结局产生负面影响。
2003年7月至2004年6月因潜在急性冠状动脉综合征就诊于急诊科的患者,根据是否同时发生创伤激活进行分层。结构化数据收集包括人口统计学、病史以及住院病程的每日跟踪。进行了30天的随访。主要结局是住院心血管并发症、30天死亡和心肌梗死的综合情况。次要结局是从分诊到进行心电图检查、转至评估室、实验室结果回报、处置决定以及实际处置的时间。
同时发生创伤激活(n = 357)和未同时发生创伤激活(n = 1235)的患者在人口统计学特征、心脏危险因素和TIMI风险评分方面相似。有和没有同时发生创伤激活的潜在急性冠状动脉综合征患者30天不良心血管事件的未调整发生率分别为6.2%和3.6%(未调整比值比1.74 [95%置信区间(CI)1.03至2.93])。在对患者病情严重程度指标(分诊分类、TIMI风险评分)和急诊科工作量(总患者护理小时数和急诊科活动)进行调整后,同时发生创伤激活与30天心血管并发症发生率增加独立相关(比值比1.72;95% CI 1.01至2.92)。
潜在急性冠状动脉综合征患者就诊时同时发生创伤激活与30天不良心血管事件发生率增加相关。虽然创伤激活可改善创伤患者的治疗,但它们可能会对需要同期资源的其他患者的治疗产生负面影响。