Soudack Michalle, Nachtigal Alicia, Vladovski Euvgeni, Brook Olga, Gaitini Diana
Department of Medical Imaging, Rambam Medical Center, Ha'aliya Hashniya 8, 31096 Haifa, Israel.
J Ultrasound Med. 2006 Oct;25(10):1271-7; quiz 1278-9. doi: 10.7863/jum.2006.25.10.1271.
The purpose of this study was to evaluate the accuracy of sonographically guided percutaneous core biopsy of soft tissue masses.
We retrospectively reviewed the medical records of patients who underwent sonographically guided biopsy of soft tissue masses at our institution during a 50-month period. Core biopsy histopathologic results were compared with surgical or clinical follow-up.
One hundred eighty-three patients, 76 male and 107 female, with a mean age of 48.5 years were included in the study. Thirteen patients had more than 1 biopsy, and the total number of biopsies performed was 196. Five patients were lost to follow-up. Biopsy results were diagnostically accurate in 174 (91%) cases. Thirteen biopsies were inconclusive. No complications occurred. The overall sensitivity, specificity, positive predictive value, and accuracy in separating malignant from benign lesions were 97%, 99%, 99%, and 98%, respectively.
Sonographically guided core needle biopsy is an accurate and safe means to obtain tissue samples for the histopathologic diagnosis of soft tissue masses. It obviates the need for open biopsy and should be performed routinely for treatment planning.
本研究旨在评估超声引导下经皮软组织肿块核心活检的准确性。
我们回顾性分析了在我院50个月期间接受超声引导下软组织肿块活检患者的病历。将核心活检组织病理学结果与手术或临床随访结果进行比较。
本研究纳入了183例患者，其中男性76例，女性107例，平均年龄48.5岁。13例患者进行了不止一次活检，共进行活检196次。5例患者失访。174例（91%）活检结果诊断准确。13例活检结果不明确。未发生并发症。在区分恶性与良性病变方面，总体敏感性、特异性、阳性预测值和准确性分别为97%、99%、99%和98%。
超声引导下核心针穿刺活检是获取软组织肿块组织样本进行组织病理学诊断的一种准确、安全的方法。它无需进行开放性活检，应作为治疗方案制定的常规检查手段。
