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孤立性动眼神经麻痹作为脑膜癌病的首发临床表现:一例报告

Isolated oculomotor nerve palsy as the presenting clinical manifestation of a meningeal carcinomatosis: a case report.

作者信息

Nardone R, Herz M, Egarter-Vigl E, Tezzon F

机构信息

Department of Neurology, F. Tappeiner Hospital, Via Rossini 5, I-39012, Merano (BZ), Italy.

出版信息

Neurol Sci. 2006 Sep;27(4):288-90. doi: 10.1007/s10072-006-0687-7.

Abstract

We present a previously unreported case of isolated oculomotor nerve palsy as the inaugural clinical sign of meningeal carcinomatosis (MC). Gadolinium-enhanced magnetic resonance images (MRI) were unremarkable. Cerebrospinal fluid (CSF) analysis showed malignant cells consistent with a pulmonary adenocarcinoma; the chest CT revealed a small pulmonary mass in the upper right lobe. This case highlights the importance of considering MC in all patients who develop sudden oculomotor palsy; lumbar punctures should always be performed on patients with normal MRI when other possible causes of oculomotor palsy have been ruled out.

摘要

我们报告一例此前未报道的孤立性动眼神经麻痹病例,其作为脑膜癌病(MC)的首发临床症状。钆增强磁共振成像(MRI)未见明显异常。脑脊液(CSF)分析显示恶性细胞,与肺腺癌相符;胸部CT显示右上叶有一个小的肺部肿块。该病例强调了在所有突发动眼神经麻痹患者中考虑MC的重要性;当动眼神经麻痹的其他可能原因被排除时,对于MRI正常的患者应始终进行腰椎穿刺。

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