Frimodt-Møller Niels, Hammerum Anette M, Bagger-Skjøt Line, Hessler Jonas Halfdan Ry, Brandt Christian T, Skov Robert L, Monnet Dominique L
Statens Serum Institut, Afdeling for Antibiotikaresistens og Sygehushygiejne.
Ugeskr Laeger. 2006 Sep 4;168(36):3039-42.
Antibiotic resistance is an increasing problem world wide, although in some areas the increase in resistance is slow, as in the Nordic countries. Multiresistant staphylococci, Enterobaceriaceae and Mycobacterium tuberculosis are already causing increased morbidity, mortality and huge costs in health budgets. New effective antibiotics will not be available for the next 10-15 years, since the pharmaceutical industry has lost interest in antibiotics. The major determinant in this field, in order to save the activity of the known antibiotics, is the control of antibiotic use.
抗生素耐药性在全球范围内是一个日益严重的问题,尽管在某些地区,如北欧国家,耐药性的增长较为缓慢。多重耐药葡萄球菌、肠杆菌科细菌和结核分枝杆菌已经导致发病率、死亡率上升,并给卫生预算带来巨大成本。由于制药行业对开发抗生素失去了兴趣,在未来10至15年内将不会有新的有效抗生素问世。为了保持已知抗生素的活性,该领域的主要决定因素是控制抗生素的使用。