Sturrock R R
Department of Anatomy and Physiology, University of Dundee, Scotland.
J Hirnforsch. 1990;31(3):399-403.
The red nucleus of the ASH/TO stain mouse brain was examined at 6, 22, 25, 28 and 31 months of age using quantitative histological techniques. Three types of neurons, large, medium and small, were identified on grounds of size and structural characteristics. The number of large neurons remained constant from 6 to 25 months of age before declining from 385 +/- 24 at 25 months to 126 +/- 12 at 31 months. The number of medium neurons remained constant from 6 to 31 months of age with an overall mean of 1139. The number of small neurons showed a slight decline at 31 months of age. The nuclear diameter of large neurons increased from 14.7 microns at 25 months to 15.6 microns at 28 months and this increase in diameter was statistically significant. The nuclear diameter of neither medium (mean 12.0 microns) nor small neurons (mean 9.6 microns) varied significantly with age.
采用定量组织学技术，在6、22、25、28和31月龄时对ASH/TO染色的小鼠脑红核进行检查。根据大小和结构特征，识别出三种类型的神经元，即大神经元、中神经元和小神经元。大神经元的数量在6至25月龄时保持恒定，然后从25月龄时的385±24下降到31月龄时的126±12。中神经元的数量在6至31月龄时保持恒定，总体平均值为1139。小神经元的数量在31月龄时略有下降。大神经元的核直径从25月龄时的14.7微米增加到28月龄时的15.6微米，这种直径增加具有统计学意义。中神经元（平均12.0微米）和小神经元（平均9.6微米）的核直径均未随年龄显著变化。
