Mashour George A
Department of Anesthesia, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
Anesth Analg. 2006 Oct;103(4):975-82. doi: 10.1213/01.ane.0000232442.69757.4a.
The nature and mechanism of human consciousness is emerging as one of the most important scientific and philosophical questions of the 21st century. Disregarded as a subject of serious inquiry throughout most of the 20th century, it has now regained legitimacy as a scientific endeavor. The investigation of consciousness and the mechanisms of general anesthesia have begun to converge. In the present article I provide an introduction to the study of consciousness, describe the neural correlates of consciousness that may be targets of general anesthetics, and suggest an integrated approach to the science of consciousness and anesthesia.
人类意识的本质和机制正成为21世纪最重要的科学和哲学问题之一。在20世纪的大部分时间里,它都被忽视,未能成为严肃的研究课题,而如今作为一项科学事业,它已重新获得了合理性。对意识的研究以及全身麻醉机制的研究已开始相互交融。在本文中,我将对意识研究进行介绍,描述可能成为全身麻醉药作用靶点的意识神经关联物,并提出一种将意识科学与麻醉学相结合的方法。