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老年人心力衰竭、抑郁症与入住养老院:一项使用倾向得分分析的观察性研究。

Geriatric heart failure, depression, and nursing home admission: an observational study using propensity score analysis.

作者信息

Ahmed Ali, Ali Mahmud, Lefante Christina M, Mullick M Syadul Islam, Kinney F Cleveland

机构信息

Division of Gerontology and Geriatric Medicine, University of Alabama at Birmingham, Birmingham, AL 35294-2041, USA.

出版信息

Am J Geriatr Psychiatry. 2006 Oct;14(10):867-75. doi: 10.1097/01.JGP.0000209639.30899.72.

Abstract

OBJECTIVE

Heart failure (HF) and depression are both common in older adults, and the presence of depression is known to worsen HF outcomes. For community-dwelling older adults, admission to a nursing home (NH) is associated with loss of independent living and poor outcomes. The objective of this study was to examine the effect of depression on NH admission for older adults with HF.

METHODS

Using the 2001-2003 National Hospital Discharge Survey datasets, the authors identified all community-dwelling older adults who were discharged alive with a primary discharge diagnosis of HF. The authors then identified those with a secondary diagnosis of depression. Using a multivariable logistic regression model, the authors then determined probability or propensity to have depression for each patient. The authors used propensity scores for depression to match all 680 depressed patients with 2,040 nondepressed patients. Finally, the authors estimated the association between depression and NH admission using bivariate and multivariable logistic regression analyses.

RESULTS

Patients had a mean (+/- standard deviation) age of 79 (+/- 8) years, 72% were women, and 9% were blacks. Compared with 17% nondepressed patients, 25% depressed patients were discharged to a NH. Depression was associated with 50% increased risk of NH admission (unadjusted relative risk [RR]: 1.50; 95% confidence interval [CI]: 1.28-1.74). The association became somewhat stronger after multivariable adjustment for various demographic and care covariates (adjusted RR: 1.60; 95% CI: 1.35-1.68).

CONCLUSION

In ambulatory older adults hospitalized with HF, a secondary diagnosis of depression was associated with a significant increased risk of NH admission.

摘要

目的

心力衰竭(HF)和抑郁症在老年人中都很常见,而且已知抑郁症的存在会使心力衰竭的预后恶化。对于居住在社区的老年人来说,入住养老院(NH)与失去独立生活能力和不良预后相关。本研究的目的是探讨抑郁症对老年心力衰竭患者入住养老院的影响。

方法

利用2001 - 2003年国家医院出院调查数据集,作者识别出所有以心力衰竭为主要出院诊断且存活出院的社区居住老年人。然后作者识别出那些有抑郁症二级诊断的患者。作者使用多变量逻辑回归模型,确定每位患者患抑郁症的概率或倾向。作者使用抑郁症倾向评分将所有680名抑郁症患者与2040名非抑郁症患者进行匹配。最后,作者使用双变量和多变量逻辑回归分析估计抑郁症与入住养老院之间的关联。

结果

患者的平均(±标准差)年龄为79(±8)岁,72%为女性,9%为黑人。与17%的非抑郁症患者相比,25%的抑郁症患者出院后入住了养老院。抑郁症与入住养老院的风险增加50%相关(未调整相对风险[RR]:1.50;95%置信区间[CI]:1.28 - 1.74)。在对各种人口统计学和护理协变量进行多变量调整后,这种关联变得更强一些(调整后RR:1.60;95% CI:1.35 - 1.68)。

结论

在因心力衰竭住院的非卧床老年人中,抑郁症二级诊断与入住养老院的风险显著增加相关。

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