Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
J Pain Symptom Manage. 2013 Oct;46(4):591-7. doi: 10.1016/j.jpainsymman.2012.10.228. Epub 2012 Dec 5.
Symptom burden has been associated with functional decline in community-dwelling older adults and may be responsive to interventions. Known predictors of nursing home (NH) admission are often nonmodifiable.
To determine if symptom burden independently predicted NH admission among community-dwelling older adults over an eight and a half-year follow-up period.
A random sample of community-dwelling Medicare beneficiaries in Alabama, stratified by race, gender, and rural/urban residence had baseline in-home assessments of sociodemographic measurements, Charlson comorbidity count, and symptoms. Symptom burden was derived from a count of 10 patient-reported symptoms. Nursing home admissions were determined from telephone interviews conducted every six months over the eight and a half years of study. Cox proportional hazard modeling was used to examine the significance of symptom burden as a predictor for NH admission after adjusting for other variables.
The mean ± SD age of the sample (N = 999) was 75.3 ± 6.7 years, and the sample was 51% rural, 50% African American, and 50% male. Thirty-eight percent (n = 380) had symptom burden scores ≥2. Seventy-five participants (7.5%) had confirmed dates for NH admission during the eight and a half years of follow-up. Using Cox proportional hazard modeling, symptom burden remained an independent predictor of time to NH placement (hazard ratio = 1.11; P = 0.02), even after adjustment for comorbidity count, race, sex, and age.
Symptom burden is an independent risk factor for NH admission. Aggressive management of symptoms in older adults may reduce or delay NH admission.
症状负担与社区居住的老年人的功能下降有关,并且可能对干预措施有反应。众所周知,养老院(NH)入院的预测因素往往是不可改变的。
确定在长达八年半的随访期间,症状负担是否独立预测社区居住的老年人 NH 入院。
阿拉巴马州的一项随机抽样社区居住的 Medicare 受益人,按种族、性别和农村/城市居住情况分层,进行基线入户评估社会人口学测量、Charlson 合并症计数和症状。症状负担是通过计算 10 项患者报告的症状得出的。养老院入院是通过在八年半的研究期间每六个月进行一次电话访谈来确定的。使用 Cox 比例风险模型来检查在调整其他变量后,症状负担作为 NH 入院预测因子的意义。
样本(N=999)的平均年龄为 75.3±6.7 岁,样本中 51%为农村人口,50%为非裔美国人,50%为男性。38%(n=380)的症状负担得分≥2。在八年半的随访期间,有 75 名参与者(7.5%)有 NH 入院的确认日期。使用 Cox 比例风险模型,即使在调整了合并症计数、种族、性别和年龄后,症状负担仍然是 NH 安置时间的独立预测因子(危险比=1.11;P=0.02)。
症状负担是 NH 入院的独立危险因素。积极管理老年人的症状可能会减少或延迟 NH 入院。