Pakarinen Mikko P, Goyal Anju, Koivusalo Antti, Baillie Colin, Turnock Rick, Rintala Risto J
Hospital for Children and Adolescents, University of Helsinki, Stenbäckinkatu 11, P.O. Box 281, 00029-HUS, Helsinki, Finland.
Pediatr Surg Int. 2006 Dec;22(12):961-5. doi: 10.1007/s00383-006-1789-2.
Optimal surgical therapy for low anorectal anomalies remains controversial. We compared functional outcome after correction of perineal fistula in boys with either anoplasty (AP) or limited posterior sagittal anorectoplasty (PSARP). Thirty-nine boys from two centres treated for perineal fistula with either AP (n = 24) or PSARP (n = 15) from 1996 to 2001 underwent prospective follow-up for functional outcome. In order to minimize heterogeneity of the study groups, only boys with perineal fistula were included. Functional outcome was assessed using a validated bowel function score (maximum score 20). Day and night time wetting as well as the age at potty training were also recorded. An independent nurse specialist interviewed caregivers. AP and PSARP groups were comparable regarding age, associated malformations and frequency of sacral dysplasia. No significant differences between the groups were observed in the overall median bowel function score, AP 18 (11-20) versus PSARP 18 (11-20), or in the age at potty training, AP 32 (14-66) versus PSARP 36 (18-60). Covering colostomy was employed significantly (P < 0.05) more often with PSARP (10/15) than with AP (1/24). Surgery for local complications was carried out significantly (P < 0.05) more often after PSARP (5/15) than after AP (2/24). Two patients in both groups required a temporary salvage colostomy. Overall functional outcome is comparable after AP and PSARP for perineal fistula in boys. As a more straightforward procedure AP is safer and less prone to complications avoiding the need for covering colostomy.
低位肛肠畸形的最佳手术治疗方案仍存在争议。我们比较了采用肛门成形术(AP)或有限后矢状肛门直肠成形术(PSARP)矫正男孩会阴瘘后的功能结局。1996年至2001年期间,来自两个中心的39名接受会阴瘘治疗的男孩,其中24名接受AP治疗,15名接受PSARP治疗,对其功能结局进行了前瞻性随访。为了尽量减少研究组的异质性,仅纳入会阴瘘男孩。使用经过验证的肠道功能评分(最高分为20分)评估功能结局。还记录了白天和夜间尿床情况以及如厕训练年龄。由一名独立的护士专家对照料者进行访谈。AP组和PSARP组在年龄、相关畸形和骶骨发育不良发生率方面具有可比性。两组在总体中位肠道功能评分方面无显著差异,AP组为18(11 - 20),PSARP组为18(11 - 20);在如厕训练年龄方面也无显著差异,AP组为32(14 - 66)个月,PSARP组为36(18 - 60)个月。PSARP组(10/15)使用覆盖性结肠造口术的频率显著高于AP组(1/24)(P < 0.05)。PSARP组(5/15)术后因局部并发症进行手术的频率显著高于AP组(2/24)(P < 0.05)。两组均有2例患者需要临时挽救性结肠造口术。对于男孩会阴瘘,AP和PSARP术后的总体功能结局相当。作为一种更直接的手术方法,AP更安全,并发症更少,无需进行覆盖性结肠造口术。