Nizard Jacky, Barbet Jacques Patrick, Ville Yves
Department of Obstetrics and Gynecology, CHIPS, Poissy, France.
Fetal Diagn Ther. 2007;22(1):33-7. doi: 10.1159/000095840. Epub 2006 Sep 21.
To compare the histological effects of diode and Neodymium-Yttrium Aluminium Garnet (Nd:YAG) laser coagulation of chorionic plate vessels.
In selected chorionic plate vessels in an ex vivo term placenta perfused with warm saline solution, diode (wavelength 940 nm) and Nd:YAG (wave length 1,064 nm) laser were used with an output of 30, 40, and 50 W, and 55 and 70 W respectively using preset energy and duration of impact. All vessels were examined histologically blindly to the procedures' characteristics.
A total of 23 vessels were coagulated. Similar histological lesions were observed using diode and Nd:YAG lasers. The lesions were compatible with an acceptable clinical effect at all power outputs tested. The results were not related to the diameter or type of vessels. Lesions of the endothelium and reduction of the vessel lumen were best achieved with a diode laser at 40 W.
Nd:YAG and Diode laser induce significant and comparable changes in chorionic plate vessels compatible with an efficient coagulation process under the experimental condition used.
比较二极管激光和钕钇铝石榴石（Nd:YAG）激光对绒毛膜板血管进行凝固的组织学效果。
在灌注温盐水溶液的离体足月胎盘的选定绒毛膜板血管中，分别使用二极管激光（波长940 nm）和Nd:YAG激光（波长1064 nm），输出功率分别为30、40和50 W以及55和70 W，采用预设的能量和照射持续时间。所有血管均在对操作特征不知情的情况下进行组织学检查。
共凝固了23条血管。使用二极管激光和Nd:YAG激光观察到类似的组织学损伤。在所有测试的功率输出下，这些损伤与可接受的临床效果相符。结果与血管的直径或类型无关。40 W的二极管激光对内皮的损伤和血管腔的缩小效果最佳。
在所用的实验条件下，Nd:YAG激光和二极管激光在绒毛膜板血管中诱导出显著且相当的变化，与有效的凝固过程相符。
