Suppr超能文献

侵袭性肺曲霉病实验性小鼠模型的标准化

Standardization of an experimental murine model of invasive pulmonary aspergillosis.

作者信息

Sheppard Donald C, Graybill John R, Najvar Laura K, Chiang Lisa Y, Doedt Thomas, Kirkpatrick William R, Bocanegra Rosie, Vallor Ana C, Patterson Thomas F, Filler Scott G

机构信息

McGill University, Department of Microbiology and Immunology, Montreal, Quebec, Canada.

出版信息

Antimicrob Agents Chemother. 2006 Oct;50(10):3501-3. doi: 10.1128/AAC.00787-06.

Abstract

Evaluating new therapeutic agents for invasive aspergillosis requires animal models that are reproducible among different laboratories. We therefore evaluated a murine model of aerosol infection in two independent laboratories and found a high level of both intra- and interlaboratory reproducibility of survival, fungal burden over time, and the efficacy of liposomal amphotericin B.

摘要

评估侵袭性曲霉病的新型治疗药物需要在不同实验室之间具有可重复性的动物模型。因此,我们在两个独立的实验室中评估了一种气溶胶感染小鼠模型,发现其在实验室内部和实验室之间的生存率、随时间变化的真菌负荷以及脂质体两性霉素B的疗效都具有很高的可重复性。

相似文献

1
Standardization of an experimental murine model of invasive pulmonary aspergillosis.
Antimicrob Agents Chemother. 2006 Oct;50(10):3501-3. doi: 10.1128/AAC.00787-06.
3
In vivo resistance of a laboratory-selected Aspergillus fumigatus isolate to amphotericin B.
Antimicrob Agents Chemother. 2005 Jan;49(1):428-30. doi: 10.1128/AAC.49.1.428-430.2005.
4
Efficacy of nebulized liposomal amphotericin B in treatment of experimental pulmonary aspergillosis.
Antimicrob Agents Chemother. 2005 Jul;49(7):3028-30. doi: 10.1128/AAC.49.7.3028-3030.2005.
5
Comparative study on the efficacy of AmBisome and Fungizone in a mouse model of pulmonary aspergillosis.
J Antimicrob Chemother. 2006 Apr;57(4):724-31. doi: 10.1093/jac/dkl005. Epub 2006 Jan 30.
6
Assessment of serum (1->3)-beta-D-glucan concentration as a measure of disease burden in a murine model of invasive pulmonary aspergillosis.
Antimicrob Agents Chemother. 2008 Mar;52(3):1176-8. doi: 10.1128/AAC.01425-07. Epub 2007 Dec 26.
7
Efficacy of ambruticin analogs in a murine model of invasive pulmonary aspergillosis.
Antimicrob Agents Chemother. 2006 Oct;50(10):3464-6. doi: 10.1128/AAC.00558-06.
10
Evaluation of SCH51048 in an experimental model of pulmonary aspergillosis.
Antimicrob Agents Chemother. 1995 Jun;39(6):1345-8. doi: 10.1128/AAC.39.6.1345.

引用本文的文献

2
Assessment of Antifungal Pharmacodynamics.
J Fungi (Basel). 2023 Feb 1;9(2):192. doi: 10.3390/jof9020192.
3
Visible-Light-Activated Molecular Machines Kill Fungi by Necrosis Following Mitochondrial Dysfunction and Calcium Overload.
Adv Sci (Weinh). 2023 Apr;10(10):e2205781. doi: 10.1002/advs.202205781. Epub 2023 Jan 30.
5
Targeting a critical step in fungal hexosamine biosynthesis.
J Biol Chem. 2020 Jun 26;295(26):8678-8691. doi: 10.1074/jbc.RA120.012985. Epub 2020 Apr 27.
6
A transcriptional signature accurately identifies Aspergillus Infection across healthy and immunosuppressed states.
Transl Res. 2020 May;219:1-12. doi: 10.1016/j.trsl.2020.02.005. Epub 2020 Feb 20.
7
What Are the Functions of Chitin Deacetylases in ?
Front Cell Infect Microbiol. 2020 Feb 6;10:28. doi: 10.3389/fcimb.2020.00028. eCollection 2020.
8
Aspergillus fumigatus and Aspergillosis in 2019.
Clin Microbiol Rev. 2019 Nov 13;33(1). doi: 10.1128/CMR.00140-18. Print 2019 Dec 18.
9
Rodent Models of Invasive Aspergillosis due to : Still a Long Path toward Standardization.
Front Microbiol. 2017 May 16;8:841. doi: 10.3389/fmicb.2017.00841. eCollection 2017.
10
Modified release itraconazole amorphous solid dispersion to treat Aspergillus fumigatus: importance of the animal model selection.
Drug Dev Ind Pharm. 2017 Feb;43(2):264-274. doi: 10.1080/03639045.2016.1236811. Epub 2016 Oct 5.

本文引用的文献

1
Comparison of three methodologies for the determination of pulmonary fungal burden in experimental murine aspergillosis.
Clin Microbiol Infect. 2006 Apr;12(4):376-80. doi: 10.1111/j.1469-0691.2005.01349.x.
2
Efficacy of caspofungin and voriconazole combinations in experimental aspergillosis.
Antimicrob Agents Chemother. 2005 Sep;49(9):3697-701. doi: 10.1128/AAC.49.9.3697-3701.2005.
5
Value of an inhalational model of invasive aspergillosis.
Med Mycol. 2004 Oct;42(5):417-25. doi: 10.1080/13693780410001712034.
6
Anti-Aspergillus fumigatus efficacy of pentraxin 3 alone and in combination with antifungals.
Antimicrob Agents Chemother. 2004 Nov;48(11):4414-21. doi: 10.1128/AAC.48.11.4414-4421.2004.
7
Novel inhalational murine model of invasive pulmonary aspergillosis.
Antimicrob Agents Chemother. 2004 May;48(5):1908-11. doi: 10.1128/AAC.48.5.1908-1911.2004.
10
Efficacy of oral saperconazole in systemic murine aspergillosis.
J Med Vet Mycol. 1995 Sep-Oct;33(5):311-7. doi: 10.1080/02681219580000631.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验