Trijbels-Smeulders Monique A J M, Kimpen Jan L L, Kollée Louis A A, Bakkers Judith, Melchers Willem, Spanjaard Lodewijk, Wannet Wim J B, Hoogkamp-Korstanje Mieke A A
Department of Paediatrics, University Medical Centre (UMC ST Radboud), Nijmegen, The Netherlands.
Pediatr Infect Dis J. 2006 Oct;25(10):945-8. doi: 10.1097/01.inf.0000237821.65559.08.
We studied the characteristics of strains isolated from neonates with group B streptococci sepsis and meningitis, before and after the introduction of antibiotic prophylaxis in The Netherlands. In 1999, 1 year after this introduction the serotype and genotype distribution and the susceptibility patterns of the GBS strains had not changed. Penicillins remain drugs of first choice to prevent and treat neonatal GBS disease.
我们研究了在荷兰引入抗生素预防措施前后，从患有B族链球菌败血症和脑膜炎的新生儿中分离出的菌株的特征。1999年，在引入该措施1年后，B族链球菌菌株的血清型和基因型分布以及药敏模式并未改变。青霉素仍然是预防和治疗新生儿B族链球菌疾病的首选药物。
