消退期结核样型和瘤型麻风皮损中的CD1阳性表皮朗格汉斯细胞
CD1-positive epidermal Langerhans cells in regressed tuberculoid and lepromatous leprosy lesions.
作者信息
Narayanan R B, Girdhar A, Girdhar B K
机构信息
Central JALMA Institute for Leprosy (ICMR), Agra, India.
出版信息
Int Arch Allergy Appl Immunol. 1990;92(1):94-6. doi: 10.1159/000235231.
A comparison was made of the numbers of epidermal Langerhans cells in active and regressed lesions of tuberculoid and lepromatous leprosy using the OKT6 and OKIa monoclonal antibodies. A reduction in the numbers of CD1+ epidermal Langerhans cells was noticed in the regressed lesions of both the tuberculoid and lepromatous leprosy lesions unlike the active lesions. The majority of infiltrates in both types of regressed lesions were HLA-DR+ and CD1-.
使用OKT6和OKIa单克隆抗体，对结核样型麻风及瘤型麻风的活动期和消退期损害的表皮朗格汉斯细胞数量进行了比较。与活动期损害不同，在结核样型和瘤型麻风的消退期损害中均发现CD1⁺表皮朗格汉斯细胞数量减少。在这两种类型的消退期损害中，大多数浸润细胞为HLA-DR⁺和CD1⁻。
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