Marinaccio A, Branchi Claudia, Massari Stefania, Scarselli A
Epidemiology Unit, Occupational Medicine Department, Italian Institute for Occupational Safety and Prevention (ISPESL).
Med Lav. 2006 May-Jun;97(3):482-7.
Italy was the main European producer of asbestos for most of the 20th century and raw asbestos imports wee also significant until the 1990's; there was a mean delay of about ten years in the pattern of asbestos consumption in Italy compared with the USA, Australia, UK and Scandinavian countries.
A national surveillance system (ReNaM) was implemented to identify cases of mesothelioma and investigate the modalities of asbestos exposure. A register of exposed workers and a database of companies presumably involved in the asbestos exposure problem was also developed. ReNaM has a regional structure and an operative centres (COR) have been established in 16 Italian regions.
The ReNaM database currently contains more than 5,000 mesothelioma cases and for 3,500 of these exposure modalities have been defined. Cases of pleural mesothelioma represent 93% of the total but there were also 334 cases of peritoneal mesothelioma, 15 of the pericardium and 14 of the tunica vaginalis of the testicle. Cases with ascertained exposure are thus distributed: 67.4% occupational exposure (ascertained, probable, possible), 4.3% domestic, 4.2% environmental and 1.3% hobby-related exposure, totalling 77.2%; 22.8% had unlikely or unknown exposure. The latency period is very long: on average 43.6 years. The register of asbestos-exposed workers contains figures on exposed workers notified to ISPESL up to 2004 and refers to the exposure period 1993-2003. The data registered cover 160 firms and about 700 workers.
A national, coordinated and uniform epidemiological surveillance system of cases of mesothelioma and the definition of asbestos exposure through active research is extremely important in identifying unexpected contaminating sources. The register of asbestos-exposed workers allows risk to be monitored and protection measures to be implemented.
在20世纪的大部分时间里,意大利是欧洲主要的石棉生产国,直到20世纪90年代,原石棉进口量也很大;与美国、澳大利亚、英国和斯堪的纳维亚国家相比,意大利的石棉消费模式平均延迟了约十年。
实施了一个国家监测系统(ReNaM),以识别间皮瘤病例并调查石棉暴露的方式。还建立了一个接触石棉工人登记册和一个可能涉及石棉暴露问题的公司数据库。ReNaM具有区域结构,在意大利的16个地区设立了运营中心(COR)。
ReNaM数据库目前包含5000多例间皮瘤病例,其中3500例已确定暴露方式。胸膜间皮瘤病例占总数的93%,但也有334例腹膜间皮瘤、15例心包间皮瘤和14例睾丸鞘膜间皮瘤。已确定暴露的病例分布如下:67.4%为职业暴露(确定、可能、可能),4.3%为家庭暴露,4.2%为环境暴露,1.3%为与爱好相关的暴露,总计77.2%;22.8%的病例暴露可能性不大或未知。潜伏期很长:平均为43.6年。石棉接触工人登记册包含截至2004年通知给意大利国家职业卫生与安全研究所(ISPESL)的接触石棉工人的数据,涉及1993 - 2003年的暴露期。登记的数据涵盖160家公司和大约700名工人。
通过积极研究建立一个全国性、协调统一的间皮瘤病例流行病学监测系统以及石棉暴露定义,对于识别意外污染源极为重要。石棉接触工人登记册有助于监测风险并实施保护措施。