Sallam Ahmed, Lynn William, McCluskey Peter, Lightman Sue
Department of Clinical Ophthalmology, Institute of Ophthalmology, Moorfields Eye Hospital, City Road, London EC1V 2PD, UK.
Expert Rev Anti Infect Ther. 2006 Aug;4(4):675-85. doi: 10.1586/14787210.4.4.675.
Intraocular Candida infections, although uncommon, represent an important clinical problem owing to the potential for visual loss, which can be bilateral. Candida chorioretinitis and endophthalmitis are complications of systemic candidiasis with extension of the fungal pathogens to the uvea and retina. Early diagnosis and prompt management significantly affect the visual prognosis for these patients. This review evaluates the current literature on Candida endophthalmitis and includes discussion on presentation, diagnosis and management strategies. New systemic and intravitreal antifungal agents are also reviewed in the context of the management of intraocular fungal infection.
眼内念珠菌感染虽不常见，但因存在视力丧失的可能性（可为双侧性）而成为一个重要的临床问题。念珠菌性脉络膜视网膜炎和眼内炎是系统性念珠菌病的并发症，真菌病原体蔓延至葡萄膜和视网膜。早期诊断和及时处理对这些患者的视力预后有显著影响。本综述评估了关于念珠菌性眼内炎的当前文献，并讨论了其临床表现、诊断和管理策略。还在眼内真菌感染的管理背景下对新型全身和玻璃体内抗真菌药物进行了综述。
