帕金森病多巴胺能治疗继发的病理性赌博

Pathological gambling secondary to dopaminergic therapy in Parkinson's disease.

作者信息

Drapier Dominique, Drapier Sophie, Sauleau Paul, Derkinderen Pascal, Damier Philippe, Allain Herve, Vérin Marc, Millet Bruno

机构信息

Service Universitaire de Psychiatrie Centre Hospitalier Guillaume Régnier, 108 Avenue du Général Leclerc, 35703 Rennes, France.

出版信息

Psychiatry Res. 2006 Nov 15;144(2-3):241-4. doi: 10.1016/j.psychres.2006.04.017. Epub 2006 Oct 2.

DOI:10.1016/j.psychres.2006.04.017

PMID:17011634

Abstract

We describe six patients with Parkinson's disease (PD) and pathological gambling. All patients started gambling after the onset of PD and initiation or increase of treatment with dopaminergic therapy. The fact that pathological behaviour disappeared as medication was ended or decreased suggests that an elaborate behavioural manifestation could be related to dopamine tone in patients with Parkinson's disease.

摘要

我们描述了6例患有帕金森病（PD）且有病态赌博行为的患者。所有患者均在帕金森病发病后，以及开始或增加多巴胺能治疗后开始赌博。随着药物治疗结束或减少，病态行为消失，这一事实表明，一种复杂的行为表现可能与帕金森病患者的多巴胺水平有关。