Grosset Katherine A, Macphee Graeme, Pal Guru, Stewart David, Watt Andrew, Davie Jim, Grosset D G
Institute of Neurological Sciences, Southern General Hospital, Glasgow, Scotland.
Mov Disord. 2006 Dec;21(12):2206-8. doi: 10.1002/mds.21110.
Excessive gambling is recognized with dopamine agonist therapy, but the prevalence is unknown. We assessed the prevalence of excess gambling by specific prospective enquiry in Parkinson's disease patients attending six West Scotland movement disorder clinics. Of 388 patients taking anti-Parkinson medication, 17 (4.4%) developed pathological gambling, all of whom were prescribed dopamine agonists. Thus, 8% of patients taking dopamine agonists had pathological gambling. Pathological gambling is not uncommon, and patients should be made aware of this potential adverse effect.
多巴胺激动剂治疗可引发过度赌博行为，但确切患病率尚不清楚。我们通过对在苏格兰西部六家运动障碍诊所就诊的帕金森病患者进行特定的前瞻性调查，评估了过度赌博的患病率。在388名服用抗帕金森药物的患者中，有17名（4.4%）出现了病理性赌博，他们均被开具了多巴胺激动剂。因此，服用多巴胺激动剂的患者中有8%患有病理性赌博。病理性赌博并不罕见，应让患者了解这种潜在的不良反应。
