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胆管肿瘤压迫的内支架姑息治疗:临床结果

Palliative treatment of bile duct tumoral compression by an endoprosthesis: clinical results.

作者信息

Sezeur A, Kracht M, Rey P, Leandri J, Fagniez P L, Farah A, Julien M, Malafosse M

机构信息

Rothschild Hospital, Paris, France.

出版信息

ASAIO Trans. 1990 Jul-Sep;36(3):M192-4.

PMID:1701317
Abstract

The palliative therapy of stenoses of the biliary tract is a difficult choice. Because percutaneous or endoscopic drainage methods are fraught with complications, an endoprosthesis for surgical intubation of the biliary tract has been developed. Thirty patients were treated by this method. After choledochotomy, the endoprosthesis is positioned surgically above the sphincter of Oddi, thereby avoiding ascending cholangitis. Twenty-nine patients (13 with gallbladder cancer, 11 with cholangiocarcinomas, 5 with metastases) presented with neoplastic compression, and one patient had an early postoperative stricture with loss of substance after right hepatectomy for hepatic metastases. The operative mortality was 3.3% (one pulmonary complication). Resolution of jaundice was obtained in all but two patients, and pruritus always resolved. The mean survival time for the patients with cholangiocarcinoma was 12.2 months and 6.33 months for those with gallbladder cancer. Indices of satisfaction (Bismuth's method) were 71% (gallbladder cancer), 93.5% (hilar cholangiocarcinoma), and 92% (metastatic compressions). This new type of surgical endoprosthesis is an alternative in the palliative treatment of neoplastic hilar compression because it is well tolerated, has a low rate of operative mortality or morbidity, and affords an acceptable quality of life for the patients.

摘要

胆道狭窄的姑息治疗是一个艰难的选择。由于经皮或内镜引流方法充满并发症,因此已开发出一种用于胆道手术插管的内置假体。30例患者接受了这种方法治疗。在胆总管切开术后,将内置假体手术放置在Oddi括约肌上方,从而避免上行性胆管炎。29例患者(13例胆囊癌、11例胆管癌、5例转移瘤)存在肿瘤压迫,1例患者在因肝转移行右肝切除术后出现早期术后狭窄并伴有组织缺失。手术死亡率为3.3%(1例肺部并发症)。除2例患者外,所有患者黄疸均消退,瘙痒也总是消退。胆管癌患者的平均生存时间为12.2个月,胆囊癌患者为6.33个月。满意度指标(Bismuth方法)分别为:胆囊癌71%,肝门部胆管癌93.5%,转移性压迫92%。这种新型手术内置假体是肿瘤性肝门压迫姑息治疗的一种替代方法,因为它耐受性良好,手术死亡率或发病率低,并且能为患者提供可接受的生活质量。

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