Witten Ilana B, Bergan Joseph F, Knudsen Eric I
Department of Neurobiology, Stanford University Medical School, Stanford, California 94305, USA.
Nat Neurosci. 2006 Nov;9(11):1439-45. doi: 10.1038/nn1781. Epub 2006 Oct 1.
The optic tectum of the barn owl contains a map of auditory space. We found that, in response to moving sounds, the locations of receptive fields that make up the map shifted toward the approaching sound. The magnitude of the receptive field shifts increased systematically with increasing stimulus velocity and, therefore, was appropriate to compensate for sensory and motor delays inherent to auditory orienting behavior. Thus, the auditory space map is not static, but shifts adaptively and dynamically in response to stimulus motion. We provide a computational model to account for these results. Because the model derives predictive responses from processes that are known to occur commonly in neural networks, we hypothesize that analogous predictive responses will be found to exist widely in the central nervous system. This hypothesis is consistent with perceptions of stimulus motion in humans for many sensory parameters.
仓鸮的视顶盖包含一张听觉空间图谱。我们发现，对于移动的声音，构成该图谱的感受野位置会朝着接近的声音方向移动。感受野移动的幅度随着刺激速度的增加而系统性增大，因此，这一现象适合于补偿听觉定向行为中固有的感觉和运动延迟。所以，听觉空间图谱并非静态，而是会随着刺激运动进行适应性和动态性的移动。我们提供了一个计算模型来解释这些结果。由于该模型从已知在神经网络中普遍存在的过程中得出预测性反应，我们推测类似的预测性反应将被广泛发现存在于中枢神经系统中。这一假设与人类对于许多感觉参数的刺激运动感知是一致的。
