Torrelo Antonio, Suárez José, Colmenero Isabel, Azorín Daniel, Perera Antonio, Zambrano Antonio
Department of Dermatology, Hospital del Niño Jesús, Madrid, Spain.
Pediatr Dermatol. 2006 Sep-Oct;23(5):484-7. doi: 10.1111/j.1525-1470.2006.00289.x.
A number of dermatoses have been reported to appear in close temporal or spatial relationship to the intramuscular injection of vaccines. We describe two young children who had morphea consistent with the deep morphea type (morphea profunda) that appeared at the site of a previous vaccination. Trauma has been implicated as an important trigger of morphea, both in children and in adults. Furthermore, vaccines might induce an immune response, which could lead to morphea in predisposed individuals.
据报道，多种皮肤病与肌肉注射疫苗在时间或空间上关系密切。我们描述了两名幼儿，他们出现了与深部硬斑病型（深部硬斑病）相符的硬斑病，出现在先前接种疫苗的部位。创伤被认为是儿童和成人硬斑病的重要触发因素。此外，疫苗可能会引发免疫反应，这可能会导致易感个体患上硬斑病。
