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伴有自身抗体和良性肿瘤的广泛深部硬斑病:一例罕见病例报告。

Extensive morphea profunda with autoantibodies and benign tumors: A rare case report.

作者信息

Budamakuntla Leelavathy, Malvankar Dipali

机构信息

Department of Dermatology STD and Leprosy, Bowring and Lady Curzon Hospitals and Bangalore Medical College and Research Institute, Bangalore, Karnataka, India.

出版信息

Indian Dermatol Online J. 2012 Sep;3(3):208-10. doi: 10.4103/2229-5178.101823.

DOI:10.4103/2229-5178.101823
PMID:23189258
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3505433/
Abstract

The term deep morphea describes a variant of morphea (localised scleroderma) in which inflammation and sclerosis are found in the deep dermis, panniculus, fascia or superficial muscle. It is sometimes associated with autoantibodies. We report the case of a 49 year-old male who had morphea profunda (radiologically and histopathologically confirmed) affecting mainly the left side of the body with face, trunk and limb involvement, along with autoantibody production and associated neurofibromas and lipomas.

摘要

深部硬斑病这一术语描述了硬斑病(局限性硬皮病)的一种变体,其中在真皮深层、皮下脂肪、筋膜或浅表肌肉中发现炎症和硬化。它有时与自身抗体有关。我们报告了一例49岁男性,患有深部硬斑病(经放射学和组织病理学证实),主要累及身体左侧,包括面部、躯干和四肢,并伴有自身抗体产生以及相关的神经纤维瘤和脂肪瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fff/3505433/4937e2e756cb/IDOJ-3-208-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fff/3505433/8f26630915a7/IDOJ-3-208-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fff/3505433/5524b16feefb/IDOJ-3-208-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fff/3505433/0cd6f3a16cbd/IDOJ-3-208-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fff/3505433/4937e2e756cb/IDOJ-3-208-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fff/3505433/8f26630915a7/IDOJ-3-208-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fff/3505433/5524b16feefb/IDOJ-3-208-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fff/3505433/0cd6f3a16cbd/IDOJ-3-208-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fff/3505433/4937e2e756cb/IDOJ-3-208-g004.jpg

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Extensive morphea profunda with autoantibodies and benign tumors: A rare case report.伴有自身抗体和良性肿瘤的广泛深部硬斑病:一例罕见病例报告。
Indian Dermatol Online J. 2012 Sep;3(3):208-10. doi: 10.4103/2229-5178.101823.
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引用本文的文献

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Morphea Profunda Masquerading as Prurigo Nodularis: An Uncommon Presentation.伪装成结节性痒疹的深部硬斑病:一种罕见的表现。
Indian J Dermatol. 2022 Jul-Aug;67(4):446-448. doi: 10.4103/ijd.ijd_211_22.

本文引用的文献

1
Parry-Romberg Syndrome Associated with Localized Scleroderma.伴局限性硬皮病的帕里-龙贝格综合征
Case Rep Neurol. 2010 Jun 1;2(2):57-62. doi: 10.1159/000314927.
2
Deep morphea.深部硬斑病
Semin Cutan Med Surg. 2007 Jun;26(2):90-5. doi: 10.1016/j.sder.2007.02.005.
3
[Diagnostic and therapeutic problems of scleroderma].[硬皮病的诊断与治疗问题]
Wiad Lek. 2006;59(5-6):392-5.
4
Deep morphea after vaccination in two young children.两名幼儿接种疫苗后出现深部硬斑病。
Pediatr Dermatol. 2006 Sep-Oct;23(5):484-7. doi: 10.1111/j.1525-1470.2006.00289.x.
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Generalized morphea.泛发性硬斑病
Dermatol Online J. 2003 Oct;9(4):24.
6
Guess what? Inflammatory disseminated morphea profunda.你猜怎么着?炎性播散性深部硬斑病。
Eur J Dermatol. 1999 Dec;9(8):654-6.
7
Classification of morphea (localized scleroderma).硬斑病(局限性硬皮病)的分类
Mayo Clin Proc. 1995 Nov;70(11):1068-76. doi: 10.4065/70.11.1068.
8
Diffuse fasciitis with hypergammaglobulinemia and eosinophilia: a new syndrome?伴有高球蛋白血症和嗜酸性粒细胞增多的弥漫性筋膜炎:一种新综合征?
J Rheumatol. 1984 Oct;11(5):569-70.
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Morphea profunda. A new concept and a histopathologic study of 23 cases.
Am J Dermatopathol. 1981 Fall;3(3):251-60. doi: 10.1097/00000372-198123000-00003.
10
Solitary morphoea profunda.孤立性深部硬斑病
Br J Dermatol. 1989 Mar;120(3):431-40. doi: 10.1111/j.1365-2133.1989.tb04171.x.