Expressive dysphasia possibly related to FK506 in two liver transplant recipients.
作者信息
Reyes J, Gayowski T, Fung J, Todo S, Alessiani M, Starzl T E
机构信息
Veterans Administration Medical Center, University of Pittsburgh.
出版信息
Transplantation. 1990 Dec;50(6):1043-5. doi: 10.1097/00007890-199012000-00028.
Abstract
摘要
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Expressive dysphasia possibly related to FK506 in two liver transplant recipients.两名肝移植受者出现可能与FK506相关的表达性失语。
Transplantation. 1990 Dec;50(6):1043-5. doi: 10.1097/00007890-199012000-00028.
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3
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Time-dependent inhibition of peptidylprolyl cis-trans-isomerases by FK506 is probably due to cis-trans isomerization of the inhibitor's imide bond.FK506对肽基脯氨酰顺反异构酶的时间依赖性抑制可能是由于抑制剂的酰亚胺键发生顺反异构化所致。
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Inhibition of FKBP rotamase activity by immunosuppressant FK506: twisted amide surrogate.
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6
Effects of immunosuppressive peptidyl-prolyl cis-trans isomerase (PPIase) inhibitors, cyclosporin A, FK506, ascomycin and rapamycin, on hair growth initiation in mouse: immunosuppression is not required for new hair growth.免疫抑制性肽基脯氨酰顺反异构酶（PPIase）抑制剂环孢菌素A、FK506、子囊霉素和雷帕霉素对小鼠毛发生长起始的影响：新毛发生长不需要免疫抑制。
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[Cyclophilin and FK506-binding protein].[亲环蛋白与FK506结合蛋白]
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8
The mechanism of action of FK 506.FK506的作用机制。
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Immunosuppression. Convergence of drug action.免疫抑制。药物作用的协同。
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A nonimmunosuppressive triene-modified rapamycin analog is a potent inhibitor of peptidyl prolyl cis-trans isomerase.
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Late onset of progressive speech impairment due to tacrolimus-associated leukoencephalopathy after kidney transplantation.肾移植后因他克莫司相关白质脑病导致的迟发性进行性言语障碍。
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Identifying risk factors for central pontine and extrapontine myelinolysis after liver transplantation: a case-control study.肝移植后脑桥中央和脑桥外髓鞘溶解症的危险因素识别：一项病例对照研究。
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Neuropsychiatric complications after liver transplantation: role of immunosuppression and hepatitis C.肝移植后的神经精神并发症：免疫抑制和丙型肝炎的作用
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Reversible tacrolimus-induced neurotoxicity isolated to the brain stem.仅局限于脑干的可逆性他克莫司诱导的神经毒性
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Cortical laminar necrosis caused by immunosuppressive therapy and chemotherapy.免疫抑制治疗和化疗引起的皮质层状坏死。
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What have we learned about primary liver transplantation under tacrolimus immunosuppression? Long-term follow-up of the first 1000 patients.关于在他克莫司免疫抑制下进行的原位肝移植，我们了解到了什么？对首批1000例患者的长期随访。
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Adverse effects of FK 506 overdosage after liver transplantation.肝移植后FK 506过量的不良反应。
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Tacrolimus. A review of its pharmacology, and therapeutic potential in hepatic and renal transplantation.他克莫司。其药理学及在肝移植和肾移植中的治疗潜力综述。
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10
Acute disseminated encephalomyelitis (ADEM) or ADEM-like inflammatory changes in a heart-lung transplant recipient: a case report.心肺移植受者发生急性播散性脑脊髓炎（ADEM）或类似ADEM的炎症性改变：一例报告
Neuroradiology. 1995 Aug;37(6):434-7. doi: 10.1007/BF00600082.
本文引用的文献
1
Association between cyclosporin neurotoxicity and hypomagnesaemia.环孢素神经毒性与低镁血症之间的关联。
Lancet. 1984 Nov 17;2(8412):1116-20. doi: 10.1016/s0140-6736(84)91556-3.
2
Liver bypass and the glia.
Res Publ Assoc Res Nerv Ment Dis. 1974;53:13-38.
3
Central nervous system toxicity after liver transplantation. The role of cyclosporine and cholesterol.肝移植后的中枢神经系统毒性。环孢素与胆固醇的作用。
N Engl J Med. 1987 Oct 1;317(14):861-6. doi: 10.1056/NEJM198710013171404.
4
Aluminium overload, a predisposing condition for epileptic seizures in renal-transplant patients treated with cyclosporin?铝过载是接受环孢素治疗的肾移植患者癫痫发作的一个诱发因素？
Lancet. 1985 Jul 20;2(8447):153-4. doi: 10.1016/s0140-6736(85)90254-5.
5
Central pontine myelinolysis after liver transplantation.
Neurology. 1989 Apr;39(4):493-8. doi: 10.1212/wnl.39.4.493.
6
Pontine and extrapontine myelinolysis following liver transplantation. Relationship to serum sodium.肝移植后桥脑和脑桥外髓鞘溶解症。与血清钠的关系。
Transplantation. 1989 Dec;48(6):1006-12. doi: 10.1097/00007890-198912000-00023.
7
A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase.免疫抑制剂FK506的一种受体是一种顺反肽基脯氨酰异构酶。
Nature. 1989 Oct 26;341(6244):758-60. doi: 10.1038/341758a0.
8
A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin.免疫抑制剂FK506的一种胞质结合蛋白具有肽基脯氨酰异构酶活性，但与亲环蛋白不同。
Nature. 1989 Oct 26;341(6244):755-7. doi: 10.1038/341755a0.
9
Cyclosporine central neurotoxicity following renal transplantation. Report of a case using magnetic resonance images.
Transplantation. 1990 Jan;49(1):215-6. doi: 10.1097/00007890-199001000-00048.
10
Liver, kidney, and thoracic organ transplantation under FK 506.在使用FK506情况下的肝脏、肾脏及胸部器官移植。
Ann Surg. 1990 Sep;212(3):295-305; discussion 306-7. doi: 10.1097/00000658-199009000-00008.
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