Makris R, Coriat P
Department of Anaesthesiology, Groupe Hospitalier Pittié-Salpêtrière, Paris, France.
Curr Opin Anaesthesiol. 2001 Feb;14(1):33-9. doi: 10.1097/00001503-200102000-00006.
Circulatory stability is one of the main objectives of the perioperative management of high-risk patients. Most of these patients are chronically treated with cardiovascular treatments, which interfere with the functioning of several physiological systems aimed at maintaining the circulatory status when the loading conditions of the heart deteriorate, or limit the compensatory mechanisms used when metabolic needs increase. Taking into account the pharmacology of these medications, their repercussions on perioperative haemodynamics and their potential beneficial effects on regional circulations, it has become possible to determine whether or not they must be given or withdrawn perioperatively.
循环稳定性是高危患者围手术期管理的主要目标之一。这些患者大多长期接受心血管治疗,当心脏负荷条件恶化时,这些治疗会干扰旨在维持循环状态的几个生理系统的功能,或者在代谢需求增加时限制所使用的代偿机制。考虑到这些药物的药理学特性、它们对围手术期血流动力学的影响以及它们对局部循环的潜在有益作用,就有可能确定在围手术期是否必须给予或停用这些药物。