Samek M, Zech D, Grond S
Klinik und Poliklinik für Zahn-, Mund- und Kieferheilkunde der Universität zu Köln.
Dtsch Zahnarztl Z. 1990 Jan;45(1):49-51.
From 1983 to 1988 57 patients with far advanced carcinomas of head and neck received pharmacological treatment of severe cancer pain according to the scheme recommended by the WHO. The evaluation of the collected data revealed that satisfactory pain control could be achieved by administration of oral analgetics. Total relief of pain was achieved in more than 35% of the days, significant relief in more than 50%. Side effects observed during therapy and co-medications are discussed.
1983年至1988年，57例头颈部晚期癌症患者按照世界卫生组织推荐的方案接受了重度癌痛的药物治疗。对收集到的数据进行评估后发现，口服镇痛药可实现令人满意的疼痛控制。超过35%的日子实现了疼痛完全缓解，超过50%的日子实现了显著缓解。文中还讨论了治疗期间观察到的副作用及辅助用药情况。
