de Carlan L, Roch P, Blanchardon E, Franck D
IRSN-Institute for Radiological Protection and Nuclear Safety, Human Radiation Protection Division, Internal Dosimetry Department, IRSN/DRPH/SDI, B.P. 17, F-92262 Fontenay-aux-Roses Cedex, France.
Radiat Prot Dosimetry. 2007;125(1-4):477-82. doi: 10.1093/rpd/ncl117. Epub 2006 Oct 3.
This article is dedicated to the application of voxel phantoms in whole-body counting calibration. The first study was performed to validate this approach using IGOR, a physical phantom dedicated to fission and activation product (FAP) measurement, and a graphical user interface, developed at the IRSN internal dose assessment laboratory, called OEDIPE (French acronym for the tool for personalised internal dose assessment) associated with the Monte Carlo code MCNP. The method was validated by comparing the results of real measurements and simulations using voxel phantoms obtained from CT scan images of IGOR. To take this application further, two studies were carried out and are presented in this article. First, a comparison was made between the IGOR voxel based phantom (IGOVOX) and a voxel human body (Zubal Phantom) to confirm whether IGOR could be considered as a realistic representation of a human. Second, the errors made when considering sources homogeneously distributed in the body were assessed against real contamination by taking into account the biokinetic behaviour of the radioactive material for two modes of exposure: the ingestion of 137Cs in soluble form and the inhalation of insoluble 60Co several days after acute incorporation.
本文致力于体素体模在全身计数校准中的应用。第一项研究旨在使用IGOR（一种专门用于裂变和活化产物（FAP）测量的物理体模）以及由法国核安全与辐射防护研究院内部剂量评估实验室开发的名为OEDIPE（个性化内部剂量评估工具的法语首字母缩写）的图形用户界面，并结合蒙特卡罗代码MCNP来验证这种方法。通过比较实际测量结果与使用从IGOR的CT扫描图像获得的体素体模进行模拟的结果，对该方法进行了验证。为了进一步推进此应用，开展了两项研究并在本文中呈现。首先，对基于IGOR体素的体模（IGOVOX）和体素人体模型（祖巴尔体模）进行了比较，以确认IGOR是否可被视为人体的真实代表。其次，通过考虑放射性物质的生物动力学行为，针对两种暴露模式下的实际污染情况，评估了在将源视为在体内均匀分布时所产生的误差：急性摄入后数天摄入可溶形式的137Cs以及吸入不溶的60Co。
