未在强直性脊柱炎和赖特综合征患者血清中检测到针对HLA - B27.5和肺炎克雷伯菌固氮酶的交叉反应抗体。 - Suppr | 超能文献

Failure to detect cross-reacting antibodies to HLA-B27.5 and Klebsiella pneumoniae nitrogenase in sera from patients with ankylosing spondylitis and Reiter's syndrome.

作者信息

de Vries D D, Dekker-Saeys A J, Gyodi E, Ivanyi P

机构信息

Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam.

出版信息

Scand J Rheumatol Suppl. 1990;87:72; discussion 72-3. doi: 10.3109/03009749009097060.

DOI:10.3109/03009749009097060

Abstract

摘要

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Failure to detect cross-reacting antibodies to HLA-B27.5 and Klebsiella pneumoniae nitrogenase in sera from patients with ankylosing spondylitis and Reiter's syndrome.未在强直性脊柱炎和赖特综合征患者血清中检测到针对HLA - B27.5和肺炎克雷伯菌固氮酶的交叉反应抗体。

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Absence of autoantibodies to peptides shared by HLA-B27.5 and Klebsiella pneumoniae nitrogenase in serum samples from HLA-B27 positive patients with ankylosing spondylitis and Reiter's syndrome.来自 HLA - B27 阳性的强直性脊柱炎和赖特综合征患者血清样本中，不存在针对 HLA - B27.5 和肺炎克雷伯菌固氮酶共有的肽段的自身抗体。

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Autoimmune pathogenesis for ankylosing spondylitis (AS) and Reiter's syndrome (RS): autoantibodies against an epitope shared by HLA B27 and Klebsiella pneumoniae nitrogenase in sera of HLA B27 patients with AS and RS.强直性脊柱炎（AS）和赖特综合征（RS）的自身免疫发病机制：AS和RS的HLA B27患者血清中存在针对HLA B27与肺炎克雷伯菌固氮酶共有的一个表位的自身抗体。

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Klebsiella pneumoniae and HLA B27-associated diseases of Reiter's syndrome and ankylosing spondylitis.肺炎克雷伯菌与赖特综合征和强直性脊柱炎等 HLA B27 相关疾病。

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Molecular mimicry between human leukocyte antigen B27 and Klebsiella. Consequences for spondyloarthropathies.人类白细胞抗原B27与克雷伯菌之间的分子模拟。对脊柱关节病的影响。

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Antibody activity in ankylosing spondylitis sera to two sites on HLA B27.1 at the MHC groove region (within sequence 65-85), and to a Klebsiella pneumoniae nitrogenase reductase peptide (within sequence 181-199).强直性脊柱炎血清中针对位于主要组织相容性复合体（MHC）沟槽区域（序列65 - 85内）的HLA B27.1两个位点以及肺炎克雷伯菌固氮酶还原酶肽（序列181 - 199内）的抗体活性。

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Autoantibodies to HLA B27 in the sera of HLA B27 patients with ankylosing spondylitis and Reiter's syndrome. Molecular mimicry with Klebsiella pneumoniae as potential mechanism of autoimmune disease.强直性脊柱炎和赖特综合征的 HLA B27 患者血清中针对 HLA B27 的自身抗体。以肺炎克雷伯菌作为自身免疫性疾病潜在机制的分子模拟。

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Cross-reactive epitope with Klebsiella pneumoniae nitrogenase in articular tissue of HLA-B27+ patients with ankylosing spondylitis.强直性脊柱炎HLA - B27阳性患者关节组织中与肺炎克雷伯菌固氮酶的交叉反应表位。

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Failure of the serological determination of HLA-B27 due to antigen masking in patients with ankylosing spondylitis.强直性脊柱炎患者中因抗原掩盖导致HLA - B27血清学检测失败。

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