Constrained least squares filtering algorithm for ultrasound image deconvolution.

A new medical ultrasound tissue model is considered in this paper, which incorporates random fluctuations of the tissue response and provides more realistic interpretation of the received pulse-echo ultrasound signal. Using this new model, we propose an algorithm for restoration of the degraded ultrasound image. The proposed deconvolution is a modification of the classical regularization technique which combines Wiener filter and the constrained least squares (LS) algorithm for restoration of the ultrasound image. The performance of the algorithm is evaluated based on both the simulated phantom images and real ultrasound radio frequency (RF) data. The results show that the algorithm can provide improved ultrasound imaging performance in terms of the resolution gain. The deconvolved images visually show better resolved tissue structures and reduce speckle, which are confirmed by a medical expert.