Sun Yi, Tian Li, Huang Yong-Fu, Sha Yi, Pei Yue-Hu
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, PR China.
Pharmazie. 2006 Sep;61(9):809-10.
A new cyclotetrapeptide, trichoderide A, was isolated from the marine fungus Trichoderma reesei. The structure was identified by spectral methods, and the stereochemical assignments were made by chiral HPLC of the hydrolyzed compound. Trichoderide A showed moderate cytotoxity against human A375-S2 melanoma cell line.