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遗传性结直肠癌风险评估中的种族和性别差异:家族史的作用。

Racial and gender disparities in hereditary colorectal cancer risk assessment: the role of family history.

作者信息

Kupfer Sonia S, McCaffrey Sarah, Kim Karen E

机构信息

Department of Gastroenterology, Univeristy of Chicago Hospitals, Chicago, IL, USA.

出版信息

J Cancer Educ. 2006 Spring;21(1 Suppl):S32-6. doi: 10.1207/s15430154jce2101s_7.

DOI:10.1207/s15430154jce2101s_7
PMID:17020499
Abstract

BACKGROUND

In this study, we aimed to examine racial/ethnic and gender differences in self-reported family cancer history knowledge in patients at high risk for hereditary colon cancer syndromes.

METHODS

We performed retrospective analysis of all referrals to the University of Chicago High Risk Colon Cancer Clinic between 1995 and 2003.

RESULTS

We found hereditary nonpolyposis colorectal cancer and familial adenomatous polyposis in 17% and 9% of Whites, respectively, and 6% and 0% of Blacks, respectively. Unknown paternal history was found in 6.5% of Whites and 18.9% of Blacks (23% men, 11% women).

CONCLUSIONS

Blacks and men had significantly decreased rates of paternal history cancer knowledge.

摘要

背景

在本研究中,我们旨在调查遗传性结肠癌综合征高危患者自我报告的家族癌症病史知识方面的种族/民族和性别差异。

方法

我们对1995年至2003年间转诊至芝加哥大学高危结肠癌诊所的所有患者进行了回顾性分析。

结果

我们分别在17%的白人以及9%的白人中发现了遗传性非息肉病性结直肠癌和家族性腺瘤性息肉病,在6%的黑人以及0%的黑人中发现了上述疾病。在6.5%的白人以及18.9%的黑人(男性为23%,女性为11%)中发现父亲病史不明。

结论

黑人和男性对父亲病史癌症的知晓率显著降低。

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