Quiroga Juan A, Castillo Inmaculada, Pardo Margarita, Rodríguez-Iñigo Elena, Carreño Vicente
Fundación para el Estudio de las Hepatitis Virales, Guzmán el Bueno 72, 28015 Madrid, Spain.
J Clin Microbiol. 2006 Dec;44(12):4559-60. doi: 10.1128/JCM.01440-06. Epub 2006 Oct 4.
A combined hepatitis C virus (HCV) antigen-antibody assay was evaluated for 115 seronegative individuals with occult HCV infection. The assay was reactive in one patient and negative to weakly reactive in three others (all four gave indeterminate results by supplemental assay) but failed to detect HCV in the remaining patients. Despite increased sensitivity the combined assay does not improve serodiagnosis of occult HCV infection.
对115例隐匿性丙型肝炎病毒(HCV)感染的血清学阴性个体进行了丙型肝炎病毒抗原 - 抗体联合检测。该检测在1例患者中呈阳性反应,在另外3例患者中呈阴性至弱阳性反应(通过补充检测,这4例结果均不确定),但在其余患者中未检测到HCV。尽管联合检测的敏感性有所提高,但它并未改善隐匿性HCV感染的血清学诊断。