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采用椎间融合器和前路钢板固定的电视辅助下L5-S1椎体滑脱前路椎间融合术。

Video-assisted ALIF with cage and anterior plate fixation for L5-S1 spondylolisthesis.

作者信息

Aunoble Stephane, Hoste David, Donkersloot Peter, Liquois Frederic, Basso Yann, Le Huec Jean-Charles

机构信息

Spine Unit, CHU Bordeaux, France.

出版信息

J Spinal Disord Tech. 2006 Oct;19(7):471-6. doi: 10.1097/01.bsd.0000211249.82823.d9.

DOI:10.1097/01.bsd.0000211249.82823.d9
PMID:17021409
Abstract

INTRODUCTION

Spondylolysis and spondylolisthesis grade 0, 1, and 2 are mainly asymptomatic but with aging process and different factors some back pain can occur and lead to chronic low back pain. The conservative treatment with physiotherapy and steroid injection is the gold standard but in some cases is not efficient enough and a surgical treatment is proposed.

OBJECTIVES

The goal of this study is to propose a new technique to treat grade 0, 1, and 2 spondylolisthesis with an anterior video-assisted fusion and stabilization.

METHODS

Twenty patients with chronic low back pain since more than 2 years and resistant to conservative therapy were included in this protocol. Clinical signs and radicular pain were noted. They were evaluated preoperatively and postoperatively until the last follow up using Oswestry score and visual analog score (VAS) for leg and back pain. X-rays showed grade 0 (8 cases), 1 (10 cases), and 2 (2 cases) spondylolisthesis according to Meyerding classification with disc collapse (bulging disc). MRI showed in all cases a disc degeneration with at least black disc and/or endplates changes with Modic I or II. All patients were operated using an anterior video-assisted retroperitoneal approach, with discectomy and fusion using an anterior impacted cage filled with autologous cancellous bone from the iliac crest and an anterior fixation with a triangular plate (Pyramid, Medtronic, Memphis). The follow up at 3, 6, 12, and 24 months was done with clinical and radiologic evaluation. In case of problem a computed tomography scan was performed.

RESULTS

There were 11 women and 9 men, with and average age of 39 years old and a BMI of 25.6. All spondylolistheses occurred at level L5. The average slippage was 19%. All L5S1 discs were black, 8 had a Modic I changes in the endplates and 2 had Modic II. The shape of L5 vertebra was abnormal (trapezoidal) in 7 cases. All anterior approaches were performed without vascular, urologic, or digestive complication. Blood loss was inferior to 100 mL. All patients had a soft brace for 8 weeks postoperatively. There was no retrograde ejaculation for the 9 men and no sexual dysfunction reported by the women. One patient had no pain relief and was reoperated for posterior pedicular screw fixation. It was obvious that there was a pseudarthrosis even after the posterior fixation and an anterior transperitoneal revision was performed with the removal of the interbody device and iliac crest bone graft packing alone. A propioni bacterium acnes germ was found responsible for the anterior nonunion. This revision surgery with antibiotics treatment was successful. One of the patients with grade 2 had an additional posterior screw fixation with a minimally invasive pedicle screw system (Sextant, Medtronic, Memphis). Nineteen patients had a good fusion at 2 years follow-up (95%), mean Oswestry score improved from 74% preoperative to 21% postoperative at the last follow-up. Visual analog score (VAS) for back pain improved from 6.5 to 2.7 and VAS for leg pain improved from 6.2 to 3.4. Satisfaction rate was 90%. All active patients except two, were back to work at an average of 5.5 months (6 wk to 1 y). The 2 patients still not working were the nonunion and a work compensation.

CONCLUSIONS

The results of this technique compare favorably with posterior stabilization and fusion (posterior lumbar interbody fusion and postero-lateral fusion) reported in the literature. Unlike posterior lumbar interbody fusion, however, it seems that the complication rate due to the approach is much lower, the fusion rate is similar. Grade 2 SPL is the limitation of the technique. The main advantage of the technique is to avoid posterior muscle damage and a quick recovery with no blood loss. Preservation of adjacent level disease can be assessed only after long-term follow-up.

摘要

引言

0级、1级和2级峡部裂及椎体滑脱通常无症状,但随着年龄增长和各种因素影响,可能会出现一些背痛并导致慢性下腰痛。物理治疗和类固醇注射的保守治疗是金标准,但在某些情况下效果不够理想,因此建议采用手术治疗。

目的

本研究的目的是提出一种新的技术,通过前路视频辅助融合与固定来治疗0级、1级和2级椎体滑脱。

方法

本研究纳入了20例慢性下腰痛超过2年且对保守治疗无效的患者。记录临床体征和神经根性疼痛。术前和术后直至最后一次随访,使用Oswestry评分和视觉模拟评分(VAS)评估腿部和背部疼痛情况。根据Meyerding分类,X线显示0级(8例)、1级(10例)和2级(2例)椎体滑脱,伴有椎间盘塌陷(椎间盘膨出)。MRI显示所有病例均存在椎间盘退变,至少有黑椎间盘和/或终板改变(Modic I或II型)。所有患者均采用前路视频辅助腹膜后入路手术,行椎间盘切除术,使用填充来自髂嵴自体松质骨的前路嵌插式椎间融合器进行融合,并使用三角钢板(Pyramid,美敦力,孟菲斯)进行前路固定。在3、6、12和24个月时进行随访,包括临床和影像学评估。如有问题,则进行计算机断层扫描。

结果

患者中11名女性,9名男性,平均年龄39岁,BMI为25.6。所有椎体滑脱均发生在L5水平。平均滑脱率为19%。所有L5S1椎间盘均为黑色,8例终板有Modic I型改变,2例有Modic II型改变。7例L5椎体形状异常(梯形)。所有前路手术均未出现血管、泌尿系统或消化系统并发症。失血量少于100 mL。所有患者术后佩戴软支具8周。9名男性均未出现逆行射精,女性均未报告性功能障碍。1例患者疼痛未缓解,再次手术行后路椎弓根螺钉固定。很明显,即使后路固定后仍存在假关节形成,遂进行前路经腹翻修手术,仅取出椎间融合器和髂嵴植骨块。发现痤疮丙酸杆菌是导致前路不愈合的原因。经抗生素治疗后,此次翻修手术成功。1例2级患者额外采用微创椎弓根螺钉系统(Sextant,美敦力,孟菲斯)进行后路螺钉固定。19例患者在2年随访时融合良好(95%),末次随访时平均Oswestry评分从术前的74%提高到术后的21%。背部疼痛的视觉模拟评分(VAS)从6.5改善至2.7,腿部疼痛的VAS从6.2改善至3.4。满意率为90%。除2例患者外,所有恢复活动的患者平均在5.5个月(6周 - 1年)后重返工作岗位。仍未工作的2例患者分别为不愈合和工伤赔偿患者。

结论

该技术的结果与文献报道的后路稳定融合术(后路腰椎椎间融合术和后外侧融合术)相比具有优势。然而,与后路腰椎椎间融合术不同的是,该手术入路导致的并发症发生率似乎要低得多,融合率相似。2级椎体滑脱是该技术的局限性。该技术的主要优点是避免了后路肌肉损伤,恢复快且无失血。只有经过长期随访才能评估对相邻节段疾病的影响。

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