Bristol Ruth E, Coons Stephen W, Rekate Harold L, Spetzler Robert F
Division of Neurological Surgery, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA.
Childs Nerv Syst. 2006 Nov;22(11):1483-6. doi: 10.1007/s00381-006-0166-8. Epub 2006 Sep 22.
An 8-year-old boy presented to the emergency department after a generalized tonic-clonic seizure that lasted for 5 min. Magnetic resonance imaging showed a 2x2 cm, intraaxial, contrast-enhanced cortical lesion in the posterior right frontal lobe. On several images the lesion appeared to be dural-based and was presumed to be a meningioma. The patient was placed on dilantin and returned 1 month later for elective surgical resection.
At surgery, a rim of intact pia was identified between the dura and the tumor. Although initial frozen-section analysis was consistent with meningioma, subsequent immunohistochemical staining and review at an outside institution established the diagnosis of intracerebral schwannoma. The patient's postoperative course was uncomplicated and he remains seizure-free with no sign of recurrence at 18 months.
Intracerebral schwannomas are uncommon cortical lesions in children. Imaging characteristics alone can be misleading; neuropathological support is essential for accurate diagnosis.
