Lee Sungjoon, Park Sung-Hye, Chung Chun Kee
Department of Neurosurgery, Seoul National University Hospital, Seoul, Korea. ; Neuroscience Research Institute, Seoul National University Medical Research Center, Seoul, Korea. ; Clinical Research Institute, Seoul National University Hospital, Seoul, Korea.
J Korean Neurosurg Soc. 2013 Oct;54(4):340-3. doi: 10.3340/jkns.2013.54.4.340. Epub 2013 Oct 31.
Intracerebral schwannomas are rare and there have been none reported in Korea. We present the case of a 25-year-old man with newly developed right-side weakness and recent seizure aggravation. His seizures started approximately 9 years prior to admission. At that time, a 1 cm diameter intra-axial enhancing mass at the left precentral gyrus was found on magnetic resonance image (MRI). After 9 years of observation and treatment with antiepileptic medication, an MRI taken due to symptom aggravation revealed peri-tumoral cyst formation with tumor enlargement. The tumor was surgically removed. Subsequently, right-side weakness diminished and there was good seizure control. Pathologic diagnosis was schwannoma. Schwannoma is a very rare tumor and there are no pathognomonic findings on radiologic images; thus, it is challenging to make a correct diagnosis. However, considering the natural course and excellent prognosis after surgical treatment of this kind of intra-axial mass with benign features, early surgery for diagnosis and proper treatment is highly recommended.
脑内神经鞘瘤较为罕见,韩国尚无相关病例报道。我们报告一例25岁男性患者,出现新发右侧肢体无力且近期癫痫发作加重。他的癫痫发作始于入院前约9年。当时,磁共振成像(MRI)显示左侧中央前回有一个直径1 cm的轴内强化肿块。经过9年的观察及抗癫痫药物治疗,因症状加重进行的MRI检查显示肿瘤周围形成囊肿且肿瘤增大。肿瘤通过手术切除。随后,右侧肢体无力症状减轻,癫痫得到良好控制。病理诊断为神经鞘瘤。神经鞘瘤是一种非常罕见的肿瘤,影像学上没有特异性表现;因此,做出正确诊断具有挑战性。然而,考虑到这种具有良性特征的轴内肿块手术治疗后的自然病程和良好预后,强烈建议早期手术以明确诊断并进行恰当治疗。