钕钇铝石榴石激光治疗缓解食管胃肿瘤

Palliation of oesophagogastric neoplasms with Nd:YAG laser treatment.

作者信息

Schulze S, Fischerman K

机构信息

Dept. of Surgery C, Rigshospitalet, University of Copenhagen, Denmark.

出版信息

Scand J Gastroenterol. 1990 Oct;25(10):1024-7. doi: 10.3109/00365529008997629.

DOI:10.3109/00365529008997629

PMID:1702230

Abstract

The palliative effect of endoscopic Nd:YAG laser treatment of malignant strictures of the oesophagus and cardia was prospectively evaluated in 30 patients. Most (n = 28) were primarily treated for dysphagia, and swallowing was improved in 21 and normalized in 14 of these patients. Two patients were successfully treated for bleeding. Six patients developed complications (including two perforations), and four of these were fatal. The median survival was 4 months (range, 17 days to 14 months). It is concluded that in a great number of patients with inoperable cancer of the oesophagus and cardia, laser treatment is better than other palliative procedures.

摘要

对30例食管和贲门恶性狭窄患者进行了前瞻性评估，以观察内镜下钕钇铝石榴石（Nd:YAG）激光治疗的姑息效果。大多数患者（n = 28）主要因吞咽困难接受治疗，其中21例患者吞咽功能改善，14例恢复正常。2例出血患者治疗成功。6例出现并发症（包括2例穿孔），其中4例死亡。中位生存期为4个月（范围为17天至14个月）。结论是，对于大量无法手术的食管癌和贲门癌患者，激光治疗优于其他姑息治疗方法。