Hahl J, Salo J, Ovaska J, Haapiainen R, Kalima T, Schröder T
Second Dept. of Surgery, Helsinki University Central Hospital, Finland.
Scand J Gastroenterol. 1991 Jan;26(1):103-8. doi: 10.3109/00365529108996490.
The clinical results of 96 patients with upper gastrointestinal malignancy have been evaluated retrospectively. Sixty-nine patients with a mean age of 72 years (35 men and 34 women) were treated with endoscopic laser therapy, and 27 patients with a mean age of 67 years (16 men and 11 women) with insertion of an oesophageal tube. After laser therapy the bulk of the tumour was reduced in 87%, and in 55% clear signs of relieved dysphagia were seen. The insertion of an oesophageal tube was successful in 89%. In the laser group no fatal complications occurred, and the overall complication risk was 8.7%. The 1-year survival in all laser patients was 12%, and in patients with impassable tumour stenosis the survival was 6%. The mortality related to the insertion of an oesophageal tube was 11%, and complications occurred in 48% of the patients. The 1-year survival of the tube group was nil. It is concluded that endoscopic laser therapy and insertion of oesophageal tube are both effective methods in palliation of oesophagogastric malignancy, but the mortality and risk for complications were markedly lower after laser therapy.
对96例上消化道恶性肿瘤患者的临床结果进行了回顾性评估。69例平均年龄72岁（35例男性和34例女性）的患者接受了内镜激光治疗，27例平均年龄67岁（16例男性和11例女性）的患者插入了食管管。激光治疗后，87%的肿瘤体积缩小，55%出现吞咽困难缓解的明显迹象。食管管插入成功率为89%。激光治疗组未发生致命并发症，总体并发症风险为8.7%。所有接受激光治疗患者的1年生存率为12%，肿瘤狭窄无法通过的患者生存率为6%。食管管插入相关死亡率为11%，48%的患者发生并发症。管组的1年生存率为零。结论是内镜激光治疗和食管管插入都是缓解食管胃恶性肿瘤的有效方法，但激光治疗后的死亡率和并发症风险明显较低。
