Alempijevic Tamara, Stimec Bojan, Kovacevic Nada
Clinic of Gastroenterology and Hepatology, Institute for Digestive Diseases, Clinical Center of Serbia, Dr Koste Todorovica 6, 11000 Belgrade, Serbia.
Surg Radiol Anat. 2006 Dec;28(6):620-4. doi: 10.1007/s00276-006-0155-3. Epub 2006 Oct 6.
Clinical expression of pancreas divisum is often explained as a consequence of relative or true stenosis of the minor papilla with dorsal duct obstruction. This anatomo-functional study of the minor papilla in pancreas divisum has included its topographical, functional and structural features.
The study was carried out on 37 human autopsy specimens of duodenopancreas, which underwent pancreatography, manometrically controlled perfusion and light microscopy.
One pancreas divisum was detected in the study group. In this case, the distances between the minor and the major papilla was 24.0 mm, and between the minor papilla and the superior duodenal flexure 27.4 mm. The minor papilla was patent when perfused under pressure of 10 mmHg, and its light microscopy revealed regular global histological organization with only light fibrosis and no cellular atypia.
The structure and position of the minor papilla in pancreas divisum did not significantly differ from the ones in fused pancreases.
胰腺分裂的临床表型常被解释为小乳头相对或真性狭窄伴背侧胰管梗阻的结果。这项关于胰腺分裂中小乳头的解剖功能研究涵盖了其地形学、功能和结构特征。
本研究对37例十二指肠胰腺的人体尸检标本进行了研究,这些标本接受了胰管造影、压力控制灌注和光学显微镜检查。
研究组中检测到1例胰腺分裂。在此病例中,小乳头与大乳头之间的距离为24.0mm,小乳头与十二指肠上曲之间的距离为27.4mm。在10mmHg压力下灌注时,小乳头通畅,光学显微镜检查显示其整体组织学结构正常,仅有轻度纤维化,无细胞异型性。
胰腺分裂中小乳头的结构和位置与融合胰腺中的小乳头结构和位置无显著差异。