Schmidt W A, Both M, Reinhold-Keller E
Rheumaklinik Berlin-Buch, Immanuel Diakonie Group, Karower Strasse 11, 13125 Berlin.
Z Rheumatol. 2006 Nov;65(7):652-6, 658-61. doi: 10.1007/s00393-006-0107-7.
In small vessel vasculitides, imaging studies aid in determining disease extent and activity, localization for biopsy, and for disease monitoring. They do not directly delineate the vasculitic lesion. Imaging studies focus on the upper and lower respiratory tract. Cranial magnetic resonance imaging (MRI) shows upper respiratory and retrobulbar granuloma in Wegener's granulomatosis. Furthermore, MRI depicts both mastoiditis and mucosal inflammation of the ear, nose, and throat. It is sensitive but not specific for the detection of cerebral vasculitis. Computed tomography (CT) reliably detects osseous facial lesions. Chest radiography in two planes remains the standard method of investigation for the lower respiratory tract. High-resolution CT aids in detecting further interstitial pathologies. Medium-sized vasculitides frequently occur with aneurysms. The classification criteria for polyarteritis nodosa involve the angiographic detection of visceral aneurysms. Patients with Kawasaki disease may develop coronary aneurysms that may be described by echocardiography or angiography according to diagnostic criteria. In large-vessel vasculitides such as temporal arteritis (giant cell arteritis) and Takayasu arteritis, MRI, MR-angiography, CT, CT-angiography, and duplex sonography delineate characteristic homogenous wall thickening with or without stenoses in the aorta and other arteries. There is a high correlation with angiography and positron emission tomography. Duplex sonography of the temporal arteries has a high sensitivity and specificity for the diagnosis. Data on temporal artery MRI in giant cell arteritis have recently been published.
在小血管血管炎中,影像学检查有助于确定疾病范围和活动度、活检部位以及疾病监测。它们不能直接描绘血管炎性病变。影像学检查聚焦于上、下呼吸道。头颅磁共振成像(MRI)可显示韦格纳肉芽肿中的上呼吸道和球后肉芽肿。此外,MRI还能显示乳突炎以及耳、鼻、喉的黏膜炎症。它对检测脑部血管炎敏感但不具有特异性。计算机断层扫描(CT)能可靠地检测面部骨质病变。胸部正侧位X线摄影仍是下呼吸道的标准检查方法。高分辨率CT有助于检测更多的间质性病变。中等大小血管炎常伴有动脉瘤。结节性多动脉炎的分类标准涉及内脏动脉瘤的血管造影检测。川崎病患者可能会出现冠状动脉瘤,可根据诊断标准通过超声心动图或血管造影进行描述。在大动脉血管炎如颞动脉炎(巨细胞动脉炎)和高安动脉炎中,MRI、磁共振血管造影、CT、CT血管造影和双功超声可描绘主动脉和其他动脉中特征性的均匀管壁增厚,有无狭窄均可显示。与血管造影和正电子发射断层扫描有高度相关性。颞动脉双功超声对诊断具有高敏感性和特异性。关于巨细胞动脉炎颞动脉MRI的数据最近已发表。