Murao T, Sunami M, Yoshioka H, Saito Y, Fujita T
Dept. of Pathology, Okayama City Hospital.
Gan No Rinsho. 1990 Dec;36(15):2611-5.
A case of an embryonal carcinoma of the retroperitoneum in a 23-year-old male is reported. His serum, urinary HCG, serum alpha-fetoprotein, and LDH values were high. After combination chemotherapy, when the tumor markers decreased to within normal values, the retroperitoneal tumor was extirpated. Histologically, a small focus in the embryonal carcinoma and cartilage was seen in the fibrous scar tissue. Immunohistochemically, the cancer cells revealed negativity for HCG, alpha-fetoprotein, and the epithelial membrane antigen. However, with the recurrence of the tumor, his HCG and LDH values elevated. The patient died 8 months after the surgical extirpation of his retroperitoneal tumor.
报告了一例23岁男性腹膜后胚胎癌病例。他的血清、尿人绒毛膜促性腺激素（HCG）、血清甲胎蛋白和乳酸脱氢酶（LDH）值均升高。联合化疗后，当肿瘤标志物降至正常范围内时，切除了腹膜后肿瘤。组织学检查显示，在纤维瘢痕组织中可见胚胎癌和软骨的小病灶。免疫组化检查显示，癌细胞对HCG、甲胎蛋白和上皮膜抗原呈阴性反应。然而，随着肿瘤复发，他的HCG和LDH值升高。该患者在腹膜后肿瘤手术切除8个月后死亡。
