Oda N, Ochiai A, Mandai K, Tahara E
Gan No Rinsho. 1987 Mar;33(3):311-6.
A case of a primary retroperitoneal tumor, combining two histologic features of embryonal carcinoma and a yolk sac tumor is reported. A 31-year-old male complained of severe abdominal pain and had a laparotomy following a diagnosis of acute panperitonitis. During the operation, a large retroperitoneal tumor attached to the abdominal aorta was found, accompanied with remarkable hemorrhage and necrosis. Histologically, the tumor showed immature large cells with a solid pattern, focally forming reticular, tubular and glomeruloid structures. PAS positive hyaline bodies, multinuclear giant cells and mitoses were noted in the tumor cells. Immunohistochemically, the tumor cells in the reticular pattern were positive for alpha-fetoprotein. No abnormality was found in the testes on palpation and ultrasound sonographic examination.
报告了一例原发性腹膜后肿瘤,其合并了胚胎癌和卵黄囊瘤的两种组织学特征。一名31岁男性因严重腹痛就诊,诊断为急性弥漫性腹膜炎后接受了剖腹手术。手术过程中,发现一个附着于腹主动脉的巨大腹膜后肿瘤,伴有明显出血和坏死。组织学检查显示,肿瘤由未成熟的大细胞构成实性结构,局部形成网状、管状和肾小球样结构。肿瘤细胞中可见PAS阳性透明小体、多核巨细胞及有丝分裂象。免疫组化检查显示,呈网状结构的肿瘤细胞甲胎蛋白呈阳性。触诊及超声检查未发现睾丸异常。