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TuBaFrost 2:为欧洲虚拟冷冻组织库网络规范组织采集与质量控制程序

TuBaFrost 2: Standardising tissue collection and quality control procedures for a European virtual frozen tissue bank network.

作者信息

Morente M M, Mager R, Alonso S, Pezzella F, Spatz A, Knox K, Kerr D, Dinjens W N M, Oosterhuis J W, Lam K H, Oomen M H A, van Damme B, van de Vijver M, van Boven H, Kerjaschki D, Pammer J, Lopez-Guerrero J A, Llombart Bosch A, Carbone A, Gloghini A, Teodorovic I, Isabelle M, Passioukov A, Lejeune S, Therasse P, van Veen E-B, Ratcliffe C, Riegman P H J

机构信息

Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro, 3, E-28029 Madrid, Spain.

出版信息

Eur J Cancer. 2006 Nov;42(16):2684-91. doi: 10.1016/j.ejca.2006.04.029. Epub 2006 Oct 5.

Abstract

Tumour Bank Networking presents a great challenge for oncological research as in order to carry out large-scale, multi-centre studies with minimal intrinsic bias, each tumour bank in the network must have some fundamental similarities and be using the same standardised and validated procedures. The European Human Frozen Tumour Tissue Bank (TuBaFrost) has responded to this need by the promotion of an integrated platform of tumour banks in Europe. The operational framework for TuBaFrost has drawn upon the best practice of standard workflows and operating procedures employed by members of the TuBaFrost project and key initiatives worldwide.

摘要

肿瘤库联网对肿瘤学研究提出了巨大挑战,因为要开展大规模、多中心研究且使内在偏倚最小化,网络中的每个肿瘤库必须具备一些基本相似之处,并采用相同的标准化且经过验证的程序。欧洲人类冷冻肿瘤组织库(TuBaFrost)通过推动欧洲肿瘤库的综合平台来应对这一需求。TuBaFrost的运营框架借鉴了TuBaFrost项目成员以及全球关键倡议所采用的标准工作流程和操作程序的最佳实践。

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