Beemath Afzal, Skaf Elias, Stein Paul D
St. Joseph Mercy Oakland Hospital, Pontiac, Michigan, USA.
Am J Cardiol. 2006 Oct 15;98(8):1073-5. doi: 10.1016/j.amjcard.2006.05.030. Epub 2006 Aug 28.
Although heart failure (HF) is a known risk factor for pulmonary embolism (PE), little is known about the frequency of death from PE in patients who die with HF. This investigation was undertaken to determine the frequency of PE as the cause of death in patients who died with HF on the basis of data from death certificates, as listed by the United States Census Bureau. Among adults with HF who died over the 19-year period of study, PE was the listed cause of death in 20,387 of 755,807 (2.7%). Assuming that the accuracy of death certificates was only 26.7%, the rate of death from PE in these patients may have been as high as 10.1%. The frequency of death from PE in patients who died with HF decreased from 1980 to 1998. In conclusion, the estimated death rate from PE in patients who died with HF is 3% to 10%. A decrease over 2 decades in the proportion of deaths from PE in such patients is compatible with the increasing and effective use of antithrombotic prophylaxis.
尽管心力衰竭（HF）是肺栓塞（PE）的已知危险因素，但对于死于HF的患者中因PE死亡的频率知之甚少。本研究旨在根据美国人口普查局列出的死亡证明数据，确定死于HF的患者中因PE导致死亡的频率。在为期19年的研究中死亡的成年HF患者中，755,807例中有20,387例（2.7%）的死亡证明列出的死因是PE。假设死亡证明的准确性仅为26.7%，这些患者中因PE死亡的比例可能高达10.1%。1980年至1998年期间，死于HF的患者中因PE死亡的频率有所下降。总之，死于HF的患者中因PE的估计死亡率为3%至10%。此类患者中因PE死亡的比例在20年期间有所下降，这与抗血栓预防措施的使用增加且有效相一致。
