Sekiuchi Makiho, Nakabayashi Kimimasa, Marumo Tomohumi, Arimura Yoshihiro, Nagasawa Toshihiko, Yamada Akira, Fujioka Yasunori
First Department of Internal Medicine, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka, 181-8611, Japan.
Mod Rheumatol. 2005;15(2):126-9. doi: 10.1007/s10165-004-0375-5.
Allergic granulomatous angiitis (AGA) is a disease entity that was first distinguished from classical polyarteritis nodosa by Churg and Strauss in 1951, and is characterized by the clinical features of allergic rhinitis or bronchial asthma, eosinophilia, and vasculitis. Allergic granulomatous angiitis has been described to mainly involve small vessels. We herein describe a case of Churg-Strauss syndrome which demonstrated the clinical and laboratory findings supporting a diagnosis of AGA and was also associated with the clinical and pathological findings for temporal arteritis, which was characterized by eosinophil infiltration and granuloma formation of the temporal artery (middle-sized vessel).
变应性肉芽肿性血管炎(AGA)是一种疾病实体,1951年由丘格(Churg)和施特劳斯(Strauss)首次从经典结节性多动脉炎中区分出来,其特征为变应性鼻炎或支气管哮喘、嗜酸性粒细胞增多以及血管炎的临床特征。变应性肉芽肿性血管炎主要累及小血管。我们在此描述一例丘格-施特劳斯综合征病例,该病例展示了支持变应性肉芽肿性血管炎诊断的临床和实验室检查结果,并且还伴有颞动脉炎的临床和病理表现,其特征为颞动脉(中等大小血管)嗜酸性粒细胞浸润和肉芽肿形成。