Roddi R, Leandri J, Hendel R G, Loisance D, Servant J M
Centre d'Expérimentation Animale et de Recherches Chirurgicales, Université Paris XII, CHU Henri-Mondor, Creteil.
Ann Chir Plast Esthet. 1990;35(4):334-7.
An experimental study was performed to evaluate the effects of tension on microsurgical anastomoses. A variable length of the common carotid artery in Wistar rats was resected to give variable degrees of tension and the artery was reanastomosed microsurgically. 42 Wistar rats were divided into 7 groups of 6 rats each according to the relative length resected. Repaired arteries were then compared histologically and functionally with the artery of the contralateral side, submitted to simple section followed by microsurgical anastomosis. Significant histological changes occurred when the length of the resected segment was greater than 13.33% of the vessel's total length. These changes included subendothelial hyperplasia, medial necrosis and thrombosis. The results of this study lead us to conclude that small degrees of tension (less than 13.33% of total vessel length in this study), have no significant effects on patency of microanastomoses. Greater tension results in changes in the laminar flow through vessels that can adversely effect patency. There are also significant histological changes that may have detrimental effects in the long term.
进行了一项实验研究以评估张力对显微外科吻合术的影响。切除Wistar大鼠一段长度可变的颈总动脉，以产生不同程度的张力，然后对该动脉进行显微外科再吻合。42只Wistar大鼠根据切除的相对长度分为7组，每组6只。然后将修复后的动脉与对侧经简单切断后再进行显微外科吻合的动脉进行组织学和功能比较。当切除段长度大于血管总长度的13.33%时，出现了显著的组织学变化。这些变化包括内皮下增生、中层坏死和血栓形成。本研究结果使我们得出结论，小程度的张力（本研究中小于血管总长度的13.33%）对显微吻合口的通畅性无显著影响。更大的张力会导致血管层流变化，可能对通畅性产生不利影响。还存在显著的组织学变化，可能长期产生有害影响。
