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[肾上腺素能和胆碱能阻断剂对成年和老年大鼠肝脏中RNA和蛋白质生物合成强度的影响]

[Effect of adrenergic and cholinergic blocking agents on the intensity of RNA and protein biosynthesis in the liver of adult and old rats].

作者信息

Bezrukov V V, Muradian Kh K

出版信息

Fiziol Zh (1978). 1990 Sep-Oct;36(5):116-20.

PMID:1703089
Abstract

The uptake of labelled precursors of RNA and protein and their incorporation into corresponding macromolecules were studied in the liver of adult and old rats after pharmacological blockade of the adreno- and cholinoreceptors. The data obtained suggest direct neural regulation of transcription and translation intensity as well as the weakening of these mechanisms in aging.

摘要

在对成年和老年大鼠的肾上腺素能和胆碱能受体进行药理学阻断后，研究了RNA和蛋白质标记前体的摄取及其掺入相应大分子的情况。所得数据表明，转录和翻译强度存在直接的神经调节，且这些机制在衰老过程中会减弱。

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