Rideout C A, McKay H A, Barr S I
Human Nutrition, University of British Columbia, 2205 East Mall, Vancouver, British Columbia, Canada V6T 1Z4.
Calcif Tissue Int. 2006 Oct;79(4):214-22. doi: 10.1007/s00223-006-0058-7. Epub 2006 Oct 10.
Girls who exercise athletically have higher bone mass than their sedentary counterparts, and this difference may be sustained in adulthood. However, whether moderate physical activity during youth confers lasting benefits for bone is unclear. We explored lifetime physical activity and current areal bone mineral density (aBMD) in 78 postmenopausal women with no known history of osteoporosis. Subjects reported physical activity for four age periods (12-18, 19-34, 35-49, > or = 50 years) using the Historical Leisure Activity Questionnaire, completed two 3-day food records, had measurements of height and weight, and aBMD assessed using dual-energy X-ray absorptiometry at the lumbar spine (L1-4) and proximal femora. Low aBMD was detected at the lumbar spine in 43 (56%) women and at the proximal femora in 38 (49%) women. Teenage physical activity, but not activity during other age periods, was associated with current aBMD at both sites (lumbar spine r = 0.31, P < 0.01; mean proximal femora r = 0.33, P < 0.01). Weight-bearing physical activity (WBPA) at age 12-18 years was the only predictor of current lumbar spine aBMD (R (2) = 0.110, P = 0.004). Current proximal femoral aBMD was positively predicted by physical activity at age 12-18 years and negatively predicted by current age (R (2) = 0.175, P = 0.001). Subjects above the median of teen WBPA had 5-8% higher current aBMD than those reporting less teen WBPA and were less likely to be classified with osteopenia or osteoporosis. Moderate physical activity during years of peak bone acquisition appears to have lasting benefits for lumbar spine and proximal femoral aBMD in postmenopausal women.
从事体育锻炼的女孩比久坐不动的同龄人骨量更高，且这种差异在成年期可能会持续存在。然而，年轻时适度的体育活动是否能为骨骼带来持久益处尚不清楚。我们对78名无骨质疏松病史的绝经后女性的终生体育活动情况和当前的骨面积密度（aBMD）进行了研究。研究对象使用历史休闲活动问卷报告了四个年龄段（12 - 18岁、19 - 34岁、35 - 49岁、≥50岁）的体育活动情况，完成了两份为期3天的饮食记录，测量了身高和体重，并使用双能X线吸收法评估了腰椎（L1 - 4）和股骨近端的aBMD。43名（56%）女性腰椎aBMD较低，38名（49%）女性股骨近端aBMD较低。青少年时期的体育活动，而非其他年龄段的活动，与两个部位当前的aBMD相关（腰椎r = 0.31，P < 0.01；股骨近端平均r = 0.33，P < 0.01）。12 - 18岁时的负重体育活动（WBPA）是当前腰椎aBMD的唯一预测因素（R (2) = 0.110，P = 0.004）。当前股骨近端aBMD由12 - 18岁时的体育活动正向预测，由当前年龄负向预测（R (2) = 0.175，P = 0.001）。青少年WBPA中位数以上的研究对象当前aBMD比青少年WBPA较少的研究对象高5 - 8%，且被归类为骨质减少或骨质疏松的可能性较小。在骨量快速增长的几年中进行适度体育活动似乎对绝经后女性的腰椎和股骨近端aBMD有持久益处。
