Wallace William E, Chen Jing-qiong, Wang Hai-jiao, Chen Wei-hong
US National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2006 Sep;24(9):537-9.
To investigate the methods of determining aluminum silicate coated on the surface of silica particles and analyze the role of surface occlusion on development of silicosis.
Respirable dust samples were collected on filters using 2 L/min flow in tungsten mines and pottery factories of Jiangxi province, and tin mines of Guanxi province. Dust particles were analyzed by a multiple-voltage scanning electron microscopy-energy dispersive X-ray spectroscopy (MVSEM-EDS) using 20 KeV and 5 KeV electron beam accelerating voltages. Changes in the silicon to aluminum X-ray line intensity ratio between the two voltages are compared particle by particle. This provided an index that distinguishes a silica particle that was homogeneously aluminum-contaminated from a clay coated silica particle.
The total of 3,982 dust particles from 47 dust samples of seven pottery factories, three tin mines and three tungsten mines were analyzed in this study. Significant difference of aluminum silicate coated on the surface of silica particle was shown between particles from pottery factories and tin mines. The average sample percentage of respirbale-sized silica particles alumino-silicate occlusion in the pottery factories (45%) was higher than that in the tin mines (18%) and tungsten mines (13%).
Higher percentages silica particles alumino-silicate occlusion is observed in the pottery factories than that in metal mines. These surface analysis results help to understand differences in risk of silicosis when exposure is normalized to cumulative respirable surface silica dust.
研究测定二氧化硅颗粒表面包覆硅酸铝的方法，并分析表面包裹对矽肺发展的作用。
在江西省的钨矿、陶瓷厂以及广西省的锡矿，以2L/min的流量用滤器采集可吸入粉尘样本。使用20keV和5keV的电子束加速电压，通过多电压扫描电子显微镜-能量色散X射线光谱仪（MVSEM-EDS）分析粉尘颗粒。逐颗粒比较两种电压下硅与铝的X射线谱线强度比的变化。这提供了一个指标，用于区分均匀被铝污染的二氧化硅颗粒和包覆有黏土的二氧化硅颗粒。
本研究分析了来自7个陶瓷厂、3个锡矿和3个钨矿的47个粉尘样本中的3982个粉尘颗粒。陶瓷厂和锡矿的颗粒在二氧化硅颗粒表面包覆的硅酸铝方面存在显著差异。陶瓷厂中可吸入大小的二氧化硅颗粒铝硅酸盐包裹的平均样本百分比（45%）高于锡矿（18%）和钨矿（13%）。
陶瓷厂中观察到的二氧化硅颗粒铝硅酸盐包裹的百分比高于金属矿。这些表面分析结果有助于理解在将接触量标准化为累积可吸入表面二氧化硅粉尘时矽肺风险的差异。
