Gaillard C, Alix E, Sallé A, Berrut G, Ritz P
Pôle de médecine interne et maladies métaboliques, Angers, France.
Clin Nutr. 2007 Feb;26(1):16-24. doi: 10.1016/j.clnu.2006.08.003. Epub 2006 Oct 10.
This review collates studies of healthy, sick, underweight (BMI < or = 21 kg/m2) and very elderly people (> or = 90 yr), in whom resting energy expenditure (REE) was measured using indirect calorimetry. We have observed the following: (1) REE, when adjusted for differences in both body weight and fat-free mass (FFM), is similar in healthy and in sick elderly people being 20 and 28 kcal/kg of FFM per day, respectively, (2) their nutritional status influences their energy requirements given that weight-adjusted REE increases in line with a decrease in BMI, (3) total energy expenditure is lower in sick elderly people given that their physical activity level, i.e. the ratio of total energy expenditure to REE, is reduced during disease averaging at 1.36, (4) energy intake (EI) being only 1.23 x REE is insufficient to cover energy requirements in sick elderly patients, whereas the EI of healthy elderly people appears sufficient to cover requirements, and finally, (5) gender ceases to be a determinant of REE in people aged 60 yr or over, with the Harris & Benedict equation capable of accurately predicting mean REE in this population, whether healthy or sick.
本综述整理了针对健康、患病、体重过轻(体重指数≤21kg/m²)及高龄(≥90岁)人群的研究,这些研究采用间接测热法测量了静息能量消耗(REE)。我们观察到以下几点:(1)在根据体重和去脂体重(FFM)差异进行调整后,健康和患病老年人的REE相似,分别为每天每千克FFM 20和28千卡;(2)他们的营养状况会影响能量需求,因为体重调整后的REE会随着体重指数的降低而增加;(3)患病老年人的总能量消耗较低,因为他们的身体活动水平,即总能量消耗与REE的比值,在患病期间会降低,平均为1.36;(4)能量摄入(EI)仅为1.23×REE,不足以满足患病老年患者的能量需求,而健康老年人的EI似乎足以满足需求;最后,(5)60岁及以上人群中,性别不再是REE的决定因素,哈里斯-本尼迪克特方程能够准确预测该人群(无论健康与否)的平均REE。