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每日使用抗菌漱口水的基本原理。

The rationale for the daily use of an antimicrobial mouthrinse.

作者信息

Barnett Michael L

机构信息

Department of Periodontics/Endodontics, School of Dental Medicine, University at Buffalo, State University of New York, USA.

出版信息

J Am Dent Assoc. 2006 Nov;137 Suppl:16S-21S. doi: 10.14219/jada.archive.2006.0408.

DOI:10.14219/jada.archive.2006.0408
PMID:17035671
Abstract

BACKGROUND

This article reviews the rationale for incorporating effective antimicrobial mouthrinses into a daily oral hygiene regimen along with mechanical plaque control methods.

TYPES OF STUDIES REVIEWED

The author reviewed studies demonstrating the essential etiologic role of a pathogenic dental plaque biofilm in the development of gingivitis, as well as studies indicating that most people fail to maintain a level of mechanical plaque control sufficient to prevent disease. In addition, he did a brief review of studies of oral microbial ecology that identified the oral mucosal tissues as a reservoir of bacteria that colonize tooth surfaces, and he summarized six-month clinical studies of marketed antimicrobial mouthrinse ingredients and products.

CONCLUSIONS

There is a twofold rationale for daily use of antimicrobial mouthrinses: first, given the inadequacy of mechanical plaque control by the majority of people, as a component added to oral hygiene regimens for the control and prevention of periodontal diseases; second, as a method of delivering antimicrobial agents to mucosal sites throughout the mouth that harbor pathogenic bacteria capable of recolonizing supragingival and subgingival tooth surfaces, thereby providing a complementary mechanism of plaque control. The efficacy of several mouthrinse ingredients and products is supported by published six-month clinical trials.

CLINICAL IMPLICATIONS

The daily use of an effective antiplaque/antigingivitis antimicrobial mouthrinse is well-supported by a scientific rationale and can be a valuable component of oral hygiene regimens.

摘要

背景

本文回顾了将有效的抗菌漱口水与机械性菌斑控制方法相结合纳入日常口腔卫生保健方案的基本原理。

综述的研究类型

作者回顾了一些研究,这些研究证明了致病性牙菌斑生物膜在牙龈炎发展中的重要病因学作用,以及表明大多数人无法维持足以预防疾病的机械性菌斑控制水平的研究。此外,他简要回顾了口腔微生物生态学的研究,这些研究将口腔黏膜组织确定为定植于牙齿表面的细菌储存库,并且他总结了市售抗菌漱口水成分和产品的六个月临床研究。

结论

每日使用抗菌漱口水有双重基本原理:第一,鉴于大多数人机械性菌斑控制不足,作为添加到口腔卫生保健方案中用于控制和预防牙周疾病的一个组成部分;第二,作为一种将抗菌剂输送到整个口腔黏膜部位的方法,这些部位存在能够重新定植于龈上和龈下牙齿表面的致病细菌,从而提供一种补充的菌斑控制机制。几种漱口水成分和产品的疗效得到了已发表的六个月临床试验的支持。

临床意义

每日使用有效的抗牙菌斑/抗牙龈炎抗菌漱口水有充分的科学依据支持,并且可以成为口腔卫生保健方案的一个有价值的组成部分。

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